Zobrazeno 1 - 10
of 190
pro vyhledávání: '"C J Helke"'
Publikováno v:
Progress in Neurobiology. 52:79-107
Placode-derived general visceral afferent neurons of the nodose ganglion transmit visceral sensory information from specialized sensory endings of the vagus nerve and its branches to the nucleus of the solitary tract. These neurons are critical in re
Publikováno v:
The FASEB Journal. 4:1606-1615
The tachykinins comprise a family of closely related peptides that participate in the regulation of diverse biological processes. The tachykinin peptides substance P, neurokinin A, neurokinin A(3-10), neuropeptide K, and neuropeptide gamma are produc
Autor:
C J, Helke, D, Verdier-Pinard
Publikováno v:
Brain research. 884(1--2)
Mature nodose and petrosal ganglia neurons (placodally derived afferent neurons of the vagal and glossopharyngeal nerves) contain TrkA and TrkC, and transport specific neurotrophins [nerve growth factor (NGF), neurotrophin-3 (NT-3), neurotrophin-4 (N
Autor:
C J, Helke, K M, Adryan, J, Fedorowicz, H, Zhuo, J S, Park, R, Curtis, H E, Radley, P S, Distefano
Publikováno v:
The Journal of comparative neurology. 393(1)
The receptor-mediated axonal transport of [125I]-labeled neurotrophins by afferent and efferent neurons of the vagus nerve was determined to predict the responsiveness of these neurons to neurotrophins in vivo. [125I]-labeled neurotrophins were admin
Publikováno v:
The Journal of comparative neurology. 379(2)
Activation of serotonin-1A receptors (5-HT(1A)R) in the medulla oblongata lowers sympathetic nerve discharge and blood pressure. Binding sites for 5-HT(1A)R ligands are present in ventral medullary nuclei [e.g., rostral ventrolateral medulla (RVLM),
Publikováno v:
Synapse (New York, N.Y.). 23(4)
Substance P (SP) nerve terminals innervate the intermediolateral cell column (IML) of the thoracic spinal cord, where SP coexists with serotonin (5-HT), neurokinin A (NKA) and thyrotropin-releasing hormone (TRH). Neither the depolarization-induced re
Autor:
V H, Routh, C J, Helke
Publikováno v:
Progress in brain research. 104
In summary, all three tachykinin receptors appear to be important modulators of physiological systems in the spinal cord. However, although there is a good deal of data concerning binding characteristics in peripheral tissues, work done in the spinal
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(3)
The presence of 5-hydroxytryptamine (5-HT)1C/2 binding sites in autonomic regions of the thoracic spinal cord and their role in the regulation of sympathetic outflow to the cardiovascular system were examined. Light microscopic receptor autoradiograp
Autor:
C J, Helke, E T, Phillips
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 245(1)
Cardiovascular and regional hemodynamic effects of the intrathecal (i.t.) administration of a thyrotropin-releasing hormone (TRH) analog, MK-771 (L-pyro-2-aminoadipyl-histidyl-thiazolidine-4-carboxamide), were studied in rats. MK-771 (0.01-5.0 microg
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 208(1)