Zobrazeno 1 - 10 of 753 pro vyhledávání: '"C J Hawkey"'
1
Hematopoietic Stem Cell Transplantation in Crohn's Disease: State-of-the-Art Treatment
Autor: C J Hawkey
Publikováno v: Digestive Diseases. 35:107-114
Both autologous and allogeneic haemopoietic stem cell transplantation (HSCT) have been tried in Crohn's disease (CD). In allogeneic HSCT, the host bone marrow is ablated and replaced by bone marrow from a donor. This substitution of a genetically dif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861dc0a9835ffe4ed1a16e474ab5f59f
https://doi.org/10.1159/000449090
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2
A monoclonal antibody reactive with human hepatocytes
Autor: Alyson Fisk, P. J. Toghill, E. B. Austin, P. G. Smith, C. H. Holmes, Barbara Gunn, C. J. Hawkey, M. J. Embleton, Robert W. Baldwin
Publikováno v: Liver. 3:295-302
A monoclonal antibody, RL23/36, reacting preferentially with a determinant expressed on normal human hepatocytes is described. Use of an immunohistochemical technique on frozen sections from a range of 75 human liver biopsy specimens revealed that th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732625e8915c85fe7b3263fe6950caf3
https://doi.org/10.1111/j.1600-0676.1983.tb00881.x
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3
NSAIDs, Coxibs, and the Intestine
Autor: C. J. Hawkey
Publikováno v: Journal of Cardiovascular Pharmacology. 47:S72-S75
Nonsteroidal anti-inflammatory drugs (NSAIDs) are capable of damaging the whole gastrointestinal tract. Small and large intestinal injuries manifest as acute changes in permeability with endoscopic erosions, chronic erosions and ulcers, diaphragms in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00199c2e4e3444db1bc6503b63b1b095
https://doi.org/10.1097/00005344-200605001-00013
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4
Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): A large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia
Autor: T. M. MacDonald, I. Ford, G. Nuki, I. S. Mackenzie, R. De Caterina, E. Findlay, J. Hallas, C. J. Hawkey, S. Ralston, M. Walters, J. Webster, J. McMurray, F. Perez Ruiz, C. G. Jennings, T. MacDonald, I. Mackenzie, C. Hawkey, F. Perez-Ruiz, A. Maseri, G. Murray, H. Bird, M. Petrie, M. MacDonald, P. Jhund, W. Saywood, R. Flynn, S. Kean
Publikováno v: Europe PubMed Central
MacDonald, T M, Ford, I, Nuki, G, Mackenzie, I S, De Caterina, R, Findlay, E, Hallas, J, Hawkey, C J, Ralston, S, Walters, M, Webster, J, McMurray, J, Perez Ruiz, F & Jennings, C G 2014, ' Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST) : a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia ', BMJ Open, vol. 4, no. 7, pp. e005354 . https://doi.org/10.1136/bmjopen-2014-005354
MacDonald, T M, Ford, I, Nuki, G, Mackenzie, I S, De Caterina, R, Findlay, E, Hallas, J, Hawkey, C J, Ralston, S, Walters, M, Webster, J, McMurray, J, Ruiz, F P & Jennings, C G 2014, ' Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia ', B M J Open, vol. 4, no. 7, e005354 . https://doi.org/10.1136/bmjopen-2014-005354
BMJ Open
Introduction: Gout affects 2.5% of the UK's adult population and is now the most common type of inflammatory arthritis. The long-term management of gout requires reduction of serum urate levels and this is most often achieved with use of xanthine oxi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8da2d78b142b7212c01e8f5196c18fe
https://acuresearchbank.acu.edu.au/item/8708y/protocol-of-the-febuxostat-versus-allopurinol-streamlined-trial-fast-a-large-prospective-randomised-open-blinded-endpoint-study-comparing-the-cardiovascular-safety-of-allopurinol-and-febuxostat-in
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5
Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis
Autor: Peter J. Dempsey, Hans Skovgaard Poulsen, C J Hawkey, Lars Damstrup, Robert J. Coffey, H. S. Wiley, S K Kuwada, Christa L. Brown
Publikováno v: British Journal of Cancer
Colonic enterocytes, like many epithelial cells in vivo, are polarized with functionally distinct apical and basolateral membrane domains. The aims of this study were to characterize the endogenous epidermal growth factor (EGF)-like ligands expressed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790d75ad1848026e1b5d6cca30c89d63
http://europepmc.org/articles/PMC2363033
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6
Elektronická kniha
Textbook of Clinical Gastroenterology and Hepatology
Autor: C. J. Hawkey, Jaime Bosch, Joel E. Richter, Guadalupe Garcia-Tsao, Francis K. L. Chan
Whereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly
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7
Varying efficacy of Helicobacter pylori eradication regimens: cost effectiveness study using a decision analysis model Commentary: Helicobacter pylori eradication in primary care
Autor: A E Duggan, K Tolley, C J Hawkey, R F A Logan, B. C Delaney, F D R. Hobbs
Publikováno v: BMJ. 316:1648-1654
Objective: To determine how small differences in the efficacy and cost of two antibiotic regimens to eradicate Helicobacter pylori can affect the overall cost effectiveness of H pylori eradication in duodenal ulcer disease. Design: A decision analysi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17c0661f1bb1be2e554047292da25392
https://doi.org/10.1136/bmj.316.7145.1648
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8
Stem cells as treatment in inflammatory bowel disease
Autor: C J Hawkey
Publikováno v: Digestive diseases (Basel, Switzerland). 30
Background: The Autologous Stem Cell Transplantation International Crohn’s Disease (ASTIC) trial is a randomised controlled evaluation of the proposition that immunoablation and haemopoietic stem cell transplantation improves the course of Crohn’
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb39798ca77bfa23ed933e0ad632ef0
https://pubmed.ncbi.nlm.nih.gov/23295704
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