Zobrazeno 1 - 10 of 23 pro vyhledávání: '"C J Groves"'
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Akademický článek
Comparison of seasonal variability in European domestic radon measurements
Autor: C. J. Groves-Kirkby, A. R. Denman, P. S. Phillips, R. G. M. Crockett, J. M. Sinclair
Publikováno v: Natural Hazards and Earth System Sciences, Vol 10, Iss 3, Pp 565-569 (2010)
Analysis of published data characterising seasonal variability of domestic radon concentrations in Europe and elsewhere shows significant variability between different countries and between regions where regional data is available. Comparison is faci
Externí odkaz: https://doaj.org/article/1d65e73464b34612b0cf51e5a869db6c
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4
Association of the CpG methylation pattern of the proximal insulin gene promoter with type 1 diabetes
Autor: Sophie Le Fur, Mark Lathrop, Diana Zelenika, Nadia Naoui, Mark I. McCarthy, Clémence Mille, Pierre Bougnères, C J Groves, Delphine Fradin
Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (5), pp.e36278. ⟨10.1371/journal.pone.0036278⟩
PLoS ONE, Vol 7, Iss 5, p e36278 (2012)
PLoS ONE, 2012, 7 (5), pp.e36278. ⟨10.1371/journal.pone.0036278⟩
The insulin (INS) region is the second most important locus associated with Type 1 Diabetes (T1D). The study of the DNA methylation pattern of the 7 CpGs proximal to the TSS in the INS gene promoter revealed that T1D patients have a lower level of me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6072457f8de806e713cd616fa6e4a8
https://ora.ox.ac.uk/objects/uuid:e7eb5940-2c79-44e1-af22-a8d4b81cc404
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6
Analysis of Multiple Data Sets Reveals No Association between the Insulin Gene Variable Number Tandem Repeat Element and Polycystic Ovary Syndrome or Related Traits
Autor: Anneli Pouta, Gerard S. Conway, Lema Haddad, Saara Taponen, Steve Franks, Karen Rush, Mark I. McCarthy, Ulla Sovio, Aimo Ruokonen, Micaela J. Goh, Eleftheria Zeggini, Anna-Liisa Hartikainen, Hannu Martikainen, C J Groves, Brenda L. Powell, Stephanie Halford, Amanda J. Bennett, Marjo-Riitta Järvelin, Neda Gharani
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 90:2988-2993
CONTEXT: Variation at the insulin gene VNTR (variable number tandem repeat) minisatellite has been reported to be associated with polycystic ovary syndrome (PCOS), but findings have been inconsistent and all studies have featured small sample sizes.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456b2d401c8c83017fd2d14bcaeb2da0
https://doi.org/10.1210/jc.2004-2485
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7
Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism
Autor: Eleftheria Zeggini, C J Groves, Stephen O'Rahilly, Desmond G. Johnston, Graham A. Hitman, Mark I. McCarthy, Mark Walker, Timothy M. Frayling, Katharine R. Owen, J C Levy, Steve Wiltshire, C.F. Liew, Andrew T. Hattersley
Publikováno v: Diabetologia. 47:2168-2175
AIMS/HYPOTHESIS: Stearoyl-CoA desaturase (SCD) is emerging as a key regulator of lipid and carbohydrate metabolism. Scd-null mice display a beneficial metabolic phenotype characterised by resistance to obesity, diabetes and hyperlipidaemia. The human
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec584782b500b18c737de763e3130ca
https://doi.org/10.1007/s00125-004-1575-4
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8
Comparison of different polymeric multimode star couplers for backplane optical interconnect
Autor: M. D. Salik, N. Shaw, Roel Baets, M. J. Goodwin, David Israel, C. J. Groves-Kirkby
Publikováno v: Journal of Lightwave Technology. 13:1057-1064
This paper describes a comparison of three types of 8/spl times/8 multimode star couplers made in polymeric multimode waveguides. Their geometry was designed with a ray tracing tool, measurements show low loss for all designs, but a symmetrical desig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10d166014d1635b7693cdaef6267f808
https://doi.org/10.1109/50.390221
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10
Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome
Autor: Rachel M. Freathy, Marjo-Riitta Järvelin, Anneli Pouta, Fredrik Karpe, A.-L. Hartikainen, Kerstin Koch, Paul Elliott, Aimo Ruokonen, Steve Franks, C J Groves, Gerard S. Conway, Ulla Sovio, Thomas M. Barber, Cecilia M. Lindgren, Amanda J. Bennett, John A.H. Wass, Hannu Martikainen, Willem H. Ouwehand, Mark I. McCarthy
Publikováno v: Diabetologia. 51(7)
AIMS/HYPOTHESIS: Variants in the fat-mass and obesity-associated gene (FTO) influence susceptibility to type 2 diabetes via an effect on adiposity/obesity. Given the important role of obesity in the aetiology of both polycystic ovary syndrome (PCOS)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181c3690e8a1d3f54fe5b2d51caa0174
https://pubmed.ncbi.nlm.nih.gov/18478198
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