Lengthening adalimumab dosing interval in quiescent Crohn’s disease patients: protocol for the pragmatic randomised non-inferiority LADI study

Autor: J Jansen, L J T Smits, R W M Pauwels, W Kievit, D J de Jong, A C de Vries, F Hoentjen, C J van der Woude, A.A. van Bodegraven, A.G.L. Bodelier, P.J. Boekema, N. de Boer, P.C.J. ter Borg, A.A. den Broeder, I.A.M Gisbertz, F.M Jansen, S.V. Jansen, D.J. de Jong, W. Kievit, R.C.A. van Linschoten, M Löwenberg, M.W.M.D. Lutgens, R.C. Mallant-Hent, A.E. van der Meulen, B. Oldenburg, R.W.M. Pauwels, M Pierik, M.J.L. Romberg-Camps, T.E.H. Römkens, M.G.V.M. Russel, L.J.T. Smits, A.C.I.T.L. Tan, M.L. Verhulst, A.C. de Vries, R.L. West, F.H.J. Wolfhagen, C.J. van der Woude

Publikováno v: BMJ Open, Vol 10, Iss 5 (2020)

Introduction Adalimumab is effective for maintenance of remission in patients with Crohn’s disease (CD) at a dose of 40 mg subcutaneously every 2 weeks. However, adalimumab is associated with (long-term) adverse events and is costly. The aim of thi

Externí odkaz: https://doaj.org/article/137bae053ba5412d9dec48e602f720d7

The diagnosis and management of CMV colitis in IBD patients shows high practice variation

Autor: R. L. Goetgebuer, C. J. van der Woude, L. Bakker, A. A. van der Eijk, L. de Ridder, A. C. de Vries

Publikováno v: Scandinavian Journal of Gastroenterology, 57(11), 1321-1326. Informa Healthcare
Scandinavian journal of gastroenterology, 57(11), 1321-1326. Informa Healthcare

Clinical guidelines on cytomegalovirus (CMV) colitis in inflammatory bowel disease (IBD) are hampered by the low quality of evidence. In this study, we aim to explore the attitude and management of CMV colitis in IBD among gastroenterologists. A web-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a3330fc5bdc001bfbd08a06b1d059c
https://pure.eur.nl/en/publications/8863e755-6af3-41f7-9072-9054a9ad73f3

Efficacy and safety of autologous adipose-derived stromal vascular fraction enriched with platelet-rich plasma in flap repair of transsphincteric cryptoglandular fistulas

Autor: R. S. Dwarkasing, E. J. R. de Graaf, W. R. Schouten, A. C. de Vries, C J van der Woude, H. P. Stevens, J. H. C. Arkenbosch, O. van Ruler, Gwenny M. Fuhler

Publikováno v: Techniques in Coloproctology
Techniques in Coloproctology, 25(12), 1301-1309. Springer-Verlag Italia

Background Transanal advancement flap repair of transsphincteric fistulas is a sphincter-preserving procedure, which frequently fails, probably due to ongoing inflammation in the remaining fistula tract. Adipose-derived stromal vascular fraction (SVF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8881bbe49a236ab96ffa97d10cff2da
http://europepmc.org/articles/PMC8580893

OP25 Prevalence of IBD in the Netherlands: development and validation of machine learning models for administrative data

Autor: R Van Linschoten, N van Leeuwen, J A Hazelzet, C J van der Woude, D van Noord, R L West

Publikováno v: Journal of Crohn's and Colitis. 17:i34-i35

Background Treatment of IBD has improved with the introduction of biologics and small molecules, yet this has come with a considerable increase in healthcare costs. Due to the increasing cost burden, reliable nationwide epidemiological data on the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81425e834d74dcf85461ca9c02842b82
https://doi.org/10.1093/ecco-jcc/jjac190.0025

P827 SARS-CoV-2 breakthrough infections after COVID-19 vaccination in patients with Inflammatory Bowel Disease: A systematic review and meta-analysis

Autor: N Van De Pol, Q Pan, L A A P Derikx, L Bakker, C J van der Woude, A C de Vries

Publikováno v: Journal of Crohn's and Colitis. 17:i960-i961

Background Patients with inflammatory bowel disease (IBD) have reduced seroconversion rates to COVID-19 vaccination. It is unclear whether an impaired immune response in vaccinated IBD patients impacts the susceptibility to SARS-CoV-2 infection and o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::674d12e7d26177225f7db798a58c991c
https://doi.org/10.1093/ecco-jcc/jjac190.0957