Výsledky vyhledávání - "C J, Stoeckert"

Retroviral Transfer of a Human Fetal Globin Gene Carrying the -202Gγβ+-HPFH Mutation into the Human Erythroleukemia Line, KMOE

Autor: C. J. Stoeckert

Publikováno v: Hemoglobin. 15:257-268

The presence of point mutations at position -202 relative to the mRNA Cap site of both human fetal gamma-globin genes is linked with elevated fetal globin levels in adults. The question addressed in this study is whether the -202 mutation affects gam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dca059d5ad717a8288201934ba3b458
https://doi.org/10.3109/03630269109027878

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Desmin/vimentin intermediate filaments are dispensable for many aspects of myogenesis

Autor: Z X Lin, T. Schultheiss, Howard Holtzer, I. Zamir, Harunori Ishikawa, C. J. Stoeckert

Publikováno v: The Journal of Cell Biology

An expression vector was prepared containing a cDNA coding for a truncated version of the intermediate filament (IF) protein desmin. The encoded truncated desmin protein lacks a portion of the highly conserved alpha-helical rod region as well as the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213523124e1d04c02ff697c828e371ff
http://europepmc.org/articles/PMC2289110

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Partial repression of human gamma-globin genes by LCR element HS3 when linked to beta-globin genes and LCR element HS2 in MEL cells

Autor: C J, Stoeckert, H, Cheng

Publikováno v: American journal of hematology. 51(3)

Clues for overcoming fetal (gamma-) globin gene repression in adult human erythroid cells may come from understanding why repression of isolated gamma-globin genes has not previously been achieved in the adult erythroid environment of mouse erythrole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8eea3ca50cc0f1eb16df0a89d1c171d
https://pubmed.ncbi.nlm.nih.gov/8619403

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Erythroid progenitors in the peripheral blood of children with sickle cell disease

Autor: T B, West, K, Ohene-Frempong, C J, Stoeckert, S, Surrey

Publikováno v: The American journal of pediatric hematology/oncology. 16(2)

The goals of this study were (a) to determine the number of peripheral blood burst forming units-erythroid (BFU-E); (b) to define the relationship between circulating BFU-E number and fetal hemoglobin (HbF) level; and (c) to define the relationship b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::940a59273405e583197bbbf3a7e55ea8
https://pubmed.ncbi.nlm.nih.gov/7513134

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A simple, efficient method for the separate isolation of RNA and DNA from the same cells

Autor: N C, Nicolaides, C J, Stoeckert

Publikováno v: BioTechniques. 8(2)

A method for the isolation of total cytoplasmic RNA and high molecular weight DNA from the same cells is described. Cells are gently lysed with NP40 in the presence of vanadyl ribonucleoside complex and the nuclei pelleted by centrifugation. RNA is p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c76194e1c63cb4c92874c87b2b3a641c
https://pubmed.ncbi.nlm.nih.gov/1690560

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Array-based analysis of gene expression: New candidates for the biological basis of normal and malignant erythroid development

Autor: L. C. Schmidt, Saul Surrey, E. Manduchi, C. R. Orr, C. J. Stoeckert, H. Ni, G. C. Overton, Steven E. McKenzie, G. R. Grant

Publikováno v: Journal of Pediatric Hematology/Oncology. 22:365

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::069637e34e8f0fff5fde1c1c0fd94f07
https://doi.org/10.1097/00043426-200007000-00019

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Akademický článek

RAD and the RAD Study-Annotator: an approach to collection, organization and exchange of all relevant information for high-throughput gene expression studies.

Autor: E. Manduchi, G. R. Grant, H. He, J. Liu, M. D. Mailman, A. D. Pizarro, P. L. Whetzel, C. J. Stoeckert

Publikováno v: Bioinformatics; Mar2004, Vol. 20 Issue 4, p452-459, 8p

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Akademický článek

Maintaining data integrity in microarray data management.

Autor: G. R. Grant, E. Manduchi, A. Pizarro, C. J. Stoeckert

Publikováno v: Biotechnology & Bioengineering; 2003, Vol. 84 Issue 7, p795-800, 6p

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Expression of the affected A gamma globin gene associated with Greek nondeletion hereditary persistence of fetal hemoglobin

Autor: C J Stoeckert, J E Metherall, M Yamakawa, J M Eisenstadt, S M Weissman, B G Forget

Publikováno v: Molecular and Cellular Biology. 7:2999-3003

The overexpressed A gamma globin gene in the Greek type of nondeletion hereditary persistence of fetal hemoglobin has a unique single-base substitution located at position -117 relative to the site of transcription initiation. This gene and its norma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a85343ac44fd60a0cf6cfa4b0c673750
https://doi.org/10.1128/mcb.7.8.2999

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Cytosine Arabinoside Plus Hemin Treatment of a Human Erythroid Cell Line, Kmoe, Strongly Induces Embryonic, Fetal, and Adult β-Like Globin Genes

Autor: Haines Km, Nicolaides Nc, C. J. Stoeckert

Publikováno v: Hemoglobin. 13:605-617

A variety of regimens were utilized on KMOE cells to maximally raise globin mRNA levels for the purpose of improving the usefullness of this line for globin gene studies. Steady-state mRNA levels of embryonic (epsilon), fetal (gamma) and adult (beta)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee878c370e5190bcbc144c6fe1d2c9ef
https://doi.org/10.3109/03630268908993111

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