Zobrazeno 1 - 6 of 6 pro vyhledávání: '"C J, Sexton"'
1
Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis
Autor: P.E. Purkis, Karin J. Purdie, C. J. Sexton, Harshad Navsaria, J. N. Stables, Irene M. Leigh, Charlotte M. Proby
Publikováno v: Experimental Dermatology. 9:104-117
A unique series of epidermal cell lines representing different stages of malignant transformation were spontaneously derived from a single adult immunosuppressed individual. Four keratinocyte lines (PM1-4) established from forehead skin are here comp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b7992514af415c2c27b6ab18ae00915
https://doi.org/10.1034/j.1600-0625.2000.009002104.x
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2
Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis
Autor: C M, Proby, K J, Purdie, C J, Sexton, P, Purkis, H A, Navsaria, J N, Stables, I M, Leigh
Publikováno v: Experimental dermatology. 9(2)
A unique series of epidermal cell lines representing different stages of malignant transformation were spontaneously derived from a single adult immunosuppressed individual. Four keratinocyte lines (PM1-4) established from forehead skin are here comp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4726fd916af8be539f0fbf1df222ee3e
https://pubmed.ncbi.nlm.nih.gov/10772384
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3
Increases in neutral, Mg2+-dependent and acidic, Mg2+-independent sphingomyelinase activities precede commitment to apoptosis and are not a consequence of caspase 3-like activity in Molt-4 cells in response to thymidylate synthase inhibition by GW1843
Autor: R M, Laethem, Y A, Hannun, S, Jayadev, C J, Sexton, J C, Strum, R, Sundseth, G K, Smith
Publikováno v: Blood. 91(11)
Thymidylate synthase (TS) inhibition causes cell death, and this enzyme is the target for the important chemotherapy regime 5-fluorouracil/leucovorin. GW1843 (1843U89) is a potent and specific folate analog TS inhibitor in clinical development. Becau
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28b5984aab7060a1c521bb237fcf6ed8
https://pubmed.ncbi.nlm.nih.gov/9596684
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4
Oral keratinocytes immortalized with the early region of human papillomavirus type 16 show elevated expression of interleukin 6, which acts as an autocrine growth factor for the derived T103C cell line
Autor: D, Bryan, C J, Sexton, D, Williams, I M, Leigh, I A, McKay
Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(10)
Interleukin 6 (IL-6) is a pleiotropic cytokine produced by cells in response to injurious stimuli including viral infections and UV light. Numerous human keratinocyte-derived lines overexpress IL-6 and have been shown to respond to IL-6 as a mitogen.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5f6953880afa1c8025e0e21013dba4c
https://pubmed.ncbi.nlm.nih.gov/8845301
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5
Malignant transformation of cutaneous lesions in renal allograft patients: a role for human papillomavirus
Autor: K J, Purdie, C J, Sexton, C M, Proby, M T, Glover, A T, Williams, J N, Stables, I M, Leigh
Publikováno v: Cancer research. 53(21)
Renal allograft recipients are at greatly increased risk of developing squamous cell carcinomas. As these frequently arise adjacent to areas of multiple viral warts, we have investigated a possible role for human papillomavirus in malignant transform
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa54f3e1ef966ab2e23956449a8106a5
https://pubmed.ncbi.nlm.nih.gov/8221669
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