Výsledky vyhledávání

[Interferon for adjuvant therapy in melanoma; although approved, not indicated]

Autor: G, Groenewegen, S, Osanto, H J, van der Rhee, C J, Punt

Publikováno v: Nederlands tijdschrift voor geneeskunde. 144(45)

The Dutch melanoma group reconsidered their 1997 consensus statement on treatment of melanoma because new studies on adjuvant treatment with interferon(IFN)-alpha have been published. These have resulted in its registration for stage IIa; for stage I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d9242dc80d9c6c8166413ac78cffb0a
https://pubmed.ncbi.nlm.nih.gov/11268915

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Trimetrexate as a biochemical modulator of 5-fluorouracil and leucovorin in colorectal cancer

Autor: C J, Punt

Publikováno v: Seminars in oncology. 27(5 Suppl 10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::06c32fc2efba490a736d0ee45926d5ff
https://pubmed.ncbi.nlm.nih.gov/11049038

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Analysis of melanoma cells in peripheral blood by reverse transcription-polymerase chain reaction for tyrosinase and MART-1 after mononuclear cell collection with cell preparation tubes: a comparison with the whole blood guanidinium isothiocyanate RNA isolation method

Autor: T J, de Vries, A, Fourkour, C J, Punt, D J, Ruiter, G N, van Muijen

Publikováno v: Melanoma research. 10(2)

Melanoma cell detection in peripheral blood by tyrosinase reverse transcription-polymerase chain reaction (RT-PCR) is usually performed on RNA isolated from whole blood using a guanidinium isothiocyanate (GITC)/phenol extraction method or from Ficoll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4d4865f3329f66ac741ba43d56240fb
https://pubmed.ncbi.nlm.nih.gov/10803712

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Dendritic cell-based vaccines: from mouse models to clinical cancer immunotherapy

Autor: M W, Schreurs, A A, Eggert, C J, Punt, C G, Figdor, G J, Adema

Publikováno v: Critical reviews in oncogenesis. 11(1)

B and T lymphocytes are the effectors of specific immunity. However, their function is critically dependent on dendritic cells (DC). DC are professional antigen presenting cells that both initiate and modulate the immune response. The recent breakthr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26c38e07bbdd3f8aa1cf4a8b524ae97b
https://pubmed.ncbi.nlm.nih.gov/10795625

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Prediction of the systemic exposure to oral 9-amino-20(S)-camptothecin using single-sample analysis

Autor: A, Sparreboom, M J, de Jonge, C J, Punt, W J, Loos, K, Nooter, G, Stoter, M G, Porro, J, Verweij

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 27(7)

The purpose of this study was to develop and validate limited-sampling strategies for prediction of the area under the plasma-concentration time curves (AUCs) of the lactone and total (i. e., lactone plus carboxylate) forms of the novel topoisomerase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cebca5a5245aa1566985fdf61b055f05
https://pubmed.ncbi.nlm.nih.gov/10383926

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Response rate and prognostic factors of recurrent oligodendroglioma treated with procarbazine, CCNU, and vincristine chemotherapy. Dutch Neuro-oncology Group

Autor: M J, van den Bent, J M, Kros, J J, Heimans, L C, Pronk, C J, van Groeningen, H G, Krouwer, M J, Taphoorn, B A, Zonnenberg, C C, Tijssen, A, Twijnstra, C J, Punt, W, Boogerd

Publikováno v: Neurology. 51(4)

To determine the response rate and factors correlated with response of oligodendroglial tumors to procarbazine, lomustine (CCNU), and vincristine (PCV) chemotherapy.Retrospective, observational multicenter study.Patients treated with PCV or intensifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::20aaec2f13f6d178cafee5f7911bf24e
https://pubmed.ncbi.nlm.nih.gov/9781544

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Pharmacokinetics and bioavailability of oral 9-aminocamptothecin capsules in adult patients with solid tumors

Autor: A, Sparreboom, M J, de Jonge, C J, Punt, K, Nooter, W J, Loos, M G, Porro, J, Verweij

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 4(8)

Preclinical studies indicate enhanced antitumor activity of 9-amino-20(S)-camptothecin (9-AC) when it is administered in a manner that provides prolonged systemic exposure. In view of this observation, the pharmacokinetics and oral bioavailability of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aafdae67baf40542ff17fff763d86cb3
https://pubmed.ncbi.nlm.nih.gov/9717819

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New drugs in the treatment of colorectal carcinoma

Autor: C J, Punt

Publikováno v: Cancer. 83(4)

Treatment with 5-fluorouracil (5-FU) plus leucovorin has been the unofficial standard therapy for patients with colorectal carcinoma (CRC) for more than a decade; however, the optimal dose and schedule remain a matter of debate. Recently several new

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8f8d76873f850890aafa4cf47260491
https://pubmed.ncbi.nlm.nih.gov/9708931

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Current status and future directions in the perioperative treatment of pancreatic cancer

Autor: D J, Wagener, C J, Punt, H, Wilke

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology. 5

Pancreatic cancer is associated with an extremely poor prognosis. Even after resection with curative intent, the 5-year survival rates usually do not exceed 5%, and neither radiotherapy (RT) nor chemotherapy (CT) improve long term survival. Because o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e10882b8e97fc69d85364b7a2b8326f
https://pubmed.ncbi.nlm.nih.gov/8204535

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