Zobrazeno 1 - 10
of 91
pro vyhledávání: '"C J, MacLean"'
Marmoset monkeys (Callithrix jacchus) with bilateral transections of the anterior temporal stem, amygdala and fornix were unable to relearn a 2-choice object discrimination first learnt prior to surgery, and were very severely impaired at relearning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1c30fc6547c90ad2c4ec67fd8ba69a
https://ora.ox.ac.uk/objects/uuid:97104cc8-36a4-43eb-a1b7-6a9fc0503321
https://ora.ox.ac.uk/objects/uuid:97104cc8-36a4-43eb-a1b7-6a9fc0503321
Autor:
Kenneth S. Kendler, Andrew C. Heath, Michael C. Neale, Ronald C. Kessler, Ellen E. Walters, C J MacLean, Lindon J. Eaves
Publikováno v:
FOCUS. 8:459-470
Objective This study was undertaken to clarify how genetic liability and stressful life events interact in the etiology of major depression. Method Information about stressful life events and onset of major depressive episodes in the past year was co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84126fa9a7506f4fb8cb8271dca31d9
https://doi.org/10.1176/foc.8.3.foc459
https://doi.org/10.1176/foc.8.3.foc459
Autor:
Brandon Wormley, Hannah Sadek, Dermot Walsh, Carole Harris-Kerr, Bharat Kadambi, Kenneth S. Kendler, Francis A. O'Neill, Richard E. Straub, Bradley T. Webb, Maxim V. Myakishev, C J MacLean, Yunlong Ma
Publikováno v:
Molecular Psychiatry. 7:542-559
From our linkage study of Irish families with a high density of schizophrenia, we have previously reported evidence for susceptibility genes in regions 5q21-31, 6p24-21, 8p22-21, and 10p15-p11. In this report, we describe the cumulative results from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43b570301a5dc82fa3bb2e8faa242c8
https://doi.org/10.1038/sj.mp.4001051
https://doi.org/10.1038/sj.mp.4001051
Publikováno v:
Neuroscience. 107:239-248
Marmoset monkeys with excitotoxic lesions confined to cornu ammonis subfields 1–3, subiculum and pre-subiculum, but sparing the entorhinal cortex, were impaired on retention and learning of conditional object–choice discriminations. For each of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3c989c43fd185737fa9dd4b3bc2943
https://doi.org/10.1016/s0306-4522(01)00358-x
https://doi.org/10.1016/s0306-4522(01)00358-x
Autor:
Harry F. Baker, Rosalind M. Ridley, María J. Ramírez, C. J. Maclean, William G. Honer, Paul T. Francis
Publikováno v:
Journal of Neural Transmission. 108:809-826
In vitro studies have consistently demonstrated a link between cholinergic neurotransmission and amyloid precursor protein metabolism, although few studies have examined such a relationship in vivo and none have been conducted in primate species. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9d8ba0fa15cee34f03f6b678e33814
https://doi.org/10.1007/s007020170031
https://doi.org/10.1007/s007020170031
Publikováno v:
Journal of Neural Transmission. 107:799-814
Cerebral beta-amyloid occurs in elderly animals of some species and in Alzheimer's disease. Previously, we injected 3 young marmosets intracerebrally with brain tissue from a patient with Alzheimer's disease. Six years later, when the monkeys were mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb234d68d14fb62ad4df353e1a4bd425
https://doi.org/10.1007/s007020070060
https://doi.org/10.1007/s007020070060
Autor:
Dermot Walsh, Richard E. Straub, R. Martin, C J MacLean, Kenneth S. Kendler, John Myers, Francis A. O'Neill, B Murphy
Publikováno v:
American Journal of Psychiatry. 157:402-408
Schizophrenia is clinically heterogeneous. Recent linkage studies suggest that multiple genes are important in the etiology of schizophrenia. The authors examined the hypothesis of whether the clinical variability in schizophrenia is due to genetic h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e427e2a8974fc25e872d1605d8ad70
https://doi.org/10.1176/appi.ajp.157.3.402
https://doi.org/10.1176/appi.ajp.157.3.402
Publikováno v:
Brain Research. 836:120-138
Monkeys with immunotoxic lesions of both the basal nucleus of Meynert and the vertical limb of the diagonal band of Broca (NBM+VDB) lost cholinergic innervation throughout the cortex and hippocampus. They were impaired at learning discriminations bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffe31b50e3462cb5c253b303eb2cd41
https://doi.org/10.1016/s0006-8993(99)01641-8
https://doi.org/10.1016/s0006-8993(99)01641-8
Autor:
Kenneth S. Kendler, C J MacLean, Declan Walsh, Yulong Ma, Richard E. Straub, Francis A. O'Neill
Publikováno v:
American Journal of Medical Genetics. 88:29-33
Linkage disequilibrium (LD) is a potentially powerful tool for the localization of disease genes for complex disorders. Most prior studies of the relationship between genetic distance and LD have examined only very short distances, focusing on the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab16edd8f27048fed55363816f152b2b
https://doi.org/10.1002/(sici)1096-8628(19990205)88:1<29::aid-ajmg5>3.0.co
https://doi.org/10.1002/(sici)1096-8628(19990205)88:1<29::aid-ajmg5>3.0.co
Publikováno v:
Behavioral Neuroscience. 113:303-315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd396496acc9195fd2111ff04501f366
https://doi.org/10.1037/0735-7044.113.2.303
https://doi.org/10.1037/0735-7044.113.2.303