Zobrazeno 1 - 3
of 3
pro vyhledávání: '"C J, Guinosso"'
Autor:
S T, Crooke, M J, Graham, J E, Zuckerman, D, Brooks, B S, Conklin, L L, Cummins, M J, Greig, C J, Guinosso, D, Kornbrust, M, Manoharan, H M, Sasmor, T, Schleich, K L, Tivel, R H, Griffey
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(2)
Biophysical and pharmacokinetic properties of five analogs of ISIS 3082, a 20-mer phosphorothioate oligodeoxynucleotide that inhibits the expression of mouse intercellular adhesion molecule 1, were evaluated. Compared to the parent compound, ISIS 308
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d2defa0c01a053d57855b82849fe768
https://pubmed.ncbi.nlm.nih.gov/8627575
https://pubmed.ncbi.nlm.nih.gov/8627575
Autor:
J W, Ellingboe, L J, Lombardo, T R, Alessi, T T, Nguyen, F, Guzzo, C J, Guinosso, J, Bullington, E N, Browne, J F, Bagli, J, Wrenn
Publikováno v:
Journal of medicinal chemistry. 36(17)
A series of naphthalenyl 3H-1,2,3,5-oxathiadiazole 2-oxides was prepared and tested for antihyperglycemic activity in the db/db mouse, a model for type 2 (non-insulin dependent) diabetes mellitus. Substitution at the 1-, 5-, or 8-positions of the nap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11713a3c5e6c6cef5b85b0f4767bef86
https://pubmed.ncbi.nlm.nih.gov/8355249
https://pubmed.ncbi.nlm.nih.gov/8355249
Autor:
B P, Monia, E A, Lesnik, C, Gonzalez, W F, Lima, D, McGee, C J, Guinosso, A M, Kawasaki, P D, Cook, S M, Freier
Publikováno v:
The Journal of biological chemistry. 268(19)
We have used a previously described 17-mer phosphorothioate (Monia, B.P., Johnston, J.F., Ecker, D. J., Zounes, M.A., Lima, W.F., and Freier, S.M. (1992) J. Biol. Chem. 267, 19954-19962) for structure-function analysis of 2'-sugar modifications inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d574443467c36beb313f59db2728b7e3
https://pubmed.ncbi.nlm.nih.gov/8390996
https://pubmed.ncbi.nlm.nih.gov/8390996