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ChemInform Abstract: Synthesis of Cyclopropyl Amino Acid Derivatives

Autor: E. W. Tan, C. M. Ward, C. J. Easton

Publikováno v: ChemInform. 23

Derivatives of α,β-methanovaline, α,β-methanophenylalanine and β-methyl-αβmethanoalanine have been prepared by regioselective side-chain functionalization of suitably protected amino acid derivatives, followed by cyclization with either sodium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54aa5c3ba43929a28f370de232dbdd6d
https://doi.org/10.1002/chin.199221264

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ChemInform Abstract: Reactions of α-Substituted Glycine Derivatives with Stannanes in the Presence of Disulfides

Autor: C. J. Easton, S. C. Peters

Publikováno v: ChemInform. 25

Reactions of α- bromo -, α- benzoyloxy - and α- methoxy -substituted glycine derivatives with stannanes afforded the corresponding α- centred glycinyl radical, which reacted with di -t-butyl disulfide and diphenyl disulfide by homolytic substitut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7ab3e49f90de5e053990fa1434dd4ea
https://doi.org/10.1002/chin.199436231

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ChemInform Abstract: Cyclodextrin and Termethylated Cyclodextrin Complexation of Aromatic Carboxylic Acids and Their Conjugate Bases in Aqueous Solution. The Effect of Size, Hydrophobicity and Charge

Autor: Stephen F. Lincoln, K. Hendrickson, C. J. Easton

Publikováno v: ChemInform. 26

For α- cyclodextrin ( αCD ), the complexation constants (K) for the formation of binary host-guest complexes ( HA.αCD ) are 750±60, 1070±60, 27±3 and 17±4 dm3 mol-1 when the guests (HA) are benzoic, 4-methylbenzoic and (R)- and (S)-2-phenylpro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2364c897de6866ee71b5f1bbc21f3b3d
https://doi.org/10.1002/chin.199539239

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Multi-component assembly of the bicyclic core associated with the tRNA synthetase inhibitors SB-203207 and SB-203208. Application to the synthesis of biologically active analogues

Autor: M G, Banwell, C F, Crasto, C J, Easton, T, Karoli, D R, March, M R, Nairn, P J, O'Hanlon, M D, Oldham, A C, Willis, W, Yue

Publikováno v: Chemical communications (Cambridge, England). (21)

The ketone (+/-)-5, which embodies the bicyclic core associated with the title tRNA synthetase inhibitors 1 and 2, has been prepared via a three-component coupling reaction involving 2-(hydroxymethyl)cyclopent-2-enone (15), methylamine (6) and propio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a1deb414aafa91200763b52df726abb
https://pubmed.ncbi.nlm.nih.gov/12240115

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