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Triarylpyrazoles with basic side chains: development of pyrazole-based estrogen receptor antagonists
Autor:
S R, Stauffer, Y R, Huang, Z D, Aron, C J, Coletta, J, Sun, B S, Katzenellenbogen, J A, Katzenellenbogen
Publikováno v:
Bioorganicmedicinal chemistry. 9(1)
Recently, we developed a novel triaryl-substituted pyrazole ligand system that has high affinity for the estrogen receptor (ER) (Fink, B. E.: Mortenson, D. S.: Stauffer, S. R.; Aron, Z. D.: Katzenellenbogen, J. A. Chem. Biol. 1999, 6, 205). Subsequen