Zobrazeno 1 - 10
of 93
pro vyhledávání: '"C I Smith"'
Autor:
D J, Brandhagen, V F, Fairbanks, W P, Baldus, C I, Smith, K E, Kruckeberg, D J, Schaid, S N, Thibodeau
Publikováno v:
American Journal of Gastroenterology. 95:2910-2914
The HFE gene contains two mutant alleles; C282Y and H63D. The C282Y mutation occurs in 55-100% of patients with hereditary hemochromatosis. The aim of our study was to re-examine the frequencies of the C282Y and H63D mutations in patients with mild a
Publikováno v:
The Journal of Immunology. 154:1265-1272
Triggering of Ag receptors on lymphocytes induces rapid phosphorylation of several receptor-associated protein tyrosine kinases (PTKs), implicating their role in controlling cellular growth and differentiation. In this study, we report the cloning of
Autor:
Dieter Häussinger, Lisa D. Pedicone, Janice K. Albrecht, Timothy R. Morgan, W. Deng, Thierry Poynard, Obaid S. Shaikh, C. I. Smith, R. Bárcena, Gunnar Norkrans, Stuart C. Gordon, Stephanos J. Hadziyannis, Ira M. Jacobson, Warren N. Schmidt, Mitchell L. Shiffman, Bruce R. Bacon, Paul J. Pockros, Clifford A. Brass, Michael P. Manns, Eugene R. Schiff, R. Esteban-Mur, Patrick Marcellin
Publikováno v:
Journal of viral hepatitis. 20(8)
Summary Sustained virologic response (SVR) is the standard measure for evaluating response to therapy in patients with chronic hepatitis C (CHC). The aim of this study was to prospectively assess the durability of SVR in the pivotal studies of pegint
Autor:
C I Smith, B Baskin, P Humire-Greiff, J N Zhou, P G Olsson, H S Maniar, P Kjellén, J D Lambris, B Christensson, L Hammarström
Publikováno v:
The Journal of Immunology. 152:557-565
The gene mutated in the human disease, X-linked agammaglobulinemia (XLA), is related to the Src gene family of cytoplasmic protein-tyrosine kinases and is designated Btk (Bruton's agammaglobulinemia tyrosine kinase; formerly Atk/Bpk; the human gene i
Publikováno v:
Journal of Experimental Biology. 182:191-206
We describe experiments on isolated, live muscle fibres which simulate their in vivo activity in a swimming saithe (Pollachius virens). Superficial fast muscle fibres isolated from points 0.35, 0.5 and 0.65bodylengths (BL) from the anterior tip had d
Publikováno v:
Journal of evolutionary biology. 23(12)
Coevolution is thought to promote evolutionary change between demes that ultimately results in speciation. If this is the case, then we should expect to see similar patterns of trait matching and phenotypic divergence between populations and between
Autor:
M, de Boer, B G, Bolscher, M C, Dinauer, S H, Orkin, C I, Smith, A, Ahlin, R S, Weening, D, Roos
Publikováno v:
Blood. 80:1553-1558
Chronic granulomatous disease (CGD) is characterized by the absence of a respiratory burst in activated phagocytes. Defects in at least four different genes lead to CGD. Patients with the X-linked form of CGD have mutations in the gene for the beta-s
Publikováno v:
The Journal of Immunology. 148:2555-2562
Serum IgG3 levels are associated with G3m allotypes in humans. However, the molecular basis of this association has not been understood. In this study we have analyzed the biologic half-life, the secretion, the cell surface expression, the cytoplasmi