Zobrazeno 1 - 10
of 71
pro vyhledávání: '"C Henrique Serezani"'
Autor:
Nathan Klopfenstein, Stephanie L Brandt, Sydney Castellanos, Matthias Gunzer, Amondrea Blackman, C Henrique Serezani
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009387 (2021)
The skin innate immune response to methicillin-resistant Staphylococcus aureus (MRSA) culminates in the formation of an abscess to prevent bacterial spread and tissue damage. Pathogen recognition receptors (PRRs) dictate the balance between microbial
Externí odkaz:
https://doaj.org/article/1779f18dc5e84c0fbac6cebf2508449d
Autor:
Stephanie L Brandt, Nathan Klopfenstein, Soujuan Wang, Seth Winfree, Brian P McCarthy, Paul R Territo, Lloyd Miller, C Henrique Serezani
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007244 (2018)
The early events that shape the innate immune response to restrain pathogens during skin infections remain elusive. Methicillin-resistant Staphylococcus aureus (MRSA) infection engages phagocyte chemotaxis, abscess formation, and microbial clearance.
Externí odkaz:
https://doaj.org/article/b671edee100040cb8d56d453493af4b1
Autor:
Zhuo Wang, Stephanie Brandt, Alexandra Medeiros, Soujuan Wang, Hao Wu, Alexander Dent, C Henrique Serezani
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115855 (2015)
Macrophages dictate both initiation and resolution of inflammation. During acute inflammation classically activated macrophages (M1) predominate, and during the resolution phase alternative macrophages (M2) are dominant. The molecular mechanisms invo
Externí odkaz:
https://doaj.org/article/d99ffa299ee04f419fd1d640f5ead9f7
Autor:
Ly Pham, Padmini Komalavilas, Alex M. Eddie, Timothy E. Thayer, Dalton L. Greenwood, Ken H. Liu, Jaclyn Weinberg, Andrew Patterson, Joshua P. Fessel, Kelli L. Boyd, Jenny C. Schafer, Jamie L. Kuck, Aaron C. Shaver, David K. Flaherty, Brittany K. Matlock, Christiaan D. M. Wijers, C. Henrique Serezani, Dean P. Jones, Evan L. Brittain, Jeffrey C. Rathmell, Michael J. Noto
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Cpt1a-dependent fatty acid beta-oxidation is found to regulate neutrophil trafficking to the site of infection in a mouse model of pneumonia and is found to play a role in pneumonia susceptibility in humans.
Externí odkaz:
https://doaj.org/article/d76a7386c54d4c2f854b839fc40b5550
Autor:
Neil T. Sprenkle, Nathan C. Winn, Kaitlyn E. Bunn, Yang Zhao, Deborah J. Park, Brenna G. Giese, John J. Karijolich, K. Mark Ansel, C. Henrique Serezani, Alyssa H. Hasty, Heather H. Pua
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112928- (2023)
Summary: Identifying molecular circuits that control adipose tissue macrophage (ATM) function is necessary to understand how ATMs contribute to tissue homeostasis and obesity-induced insulin resistance. In this study, we find that mice with a myeloid
Externí odkaz:
https://doaj.org/article/818abb9941584f42ae9b426fc3080508
Autor:
Michelle L. Korir, Ryan S. Doster, Jacky Lu, Miriam A. Guevara, Sabrina K. Spicer, Rebecca E. Moore, Jamisha D. Francis, Lisa M. Rogers, Kathryn P. Haley, Amondrea Blackman, Kristen N. Noble, Alison J. Eastman, Janice A. Williams, Steven M. Damo, Kelli L. Boyd, Steven D. Townsend, C. Henrique Serezani, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Perinatal infection with Group B Streptococcus (GBS) is associated with preterm birth, neonatal sepsis, and stillbirth. Here, Korir et al. show that gene cadD, encoding a putative metal efflux transporter, is important for metal detoxification, immun
Externí odkaz:
https://doaj.org/article/597dc8cb42f34cfcbcc7b2c564bd3327
Autor:
Cara Lang, Sohini Roy, Yu Wang, Diana Graves, Yaomin Xu, C. Henrique Serezani, Michael Korrer, Young J. Kim
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Caspase-1 signaling in myeloid suppressor cells can promote T-cell independent cancer progression, but the regulation of inflammasome signaling within the highly heterogeneous myeloid population in the tumor milieu remains elusive. To resolve this co
Externí odkaz:
https://doaj.org/article/8afb072ac409417e812c9720a0d5d7ee
Autor:
Icaro Bonyek-Silva, Thiago Cerqueira-Silva, Sara Nunes, Antônio Fernando Araújo Machado, Márcio Rivison Silva Cruz, Blenda Pereira, Leilane Estrela, Jéssica Silva, Ananda Isis, Aldina Barral, Pablo Rafael Silveira Oliveira, Ricardo Khouri, C. Henrique Serezani, Cláudia Brodskyn, Juliana Ribeiro Caldas, Manoel Barral-Netto, Viviane Boaventura, Natalia Machado Tavares
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
AimsPre-existing conditions, such as age, hypertension, obesity, and diabetes, constitute known risk factors for severe COVID-19. However, the impact of prediabetes mellitus (PDM) on COVID-19 severity is less clear. This study aimed to evaluate the i
Externí odkaz:
https://doaj.org/article/43327780847a41ff914ca9eb3dc8da9d
Autor:
Pegah Mehrpouya-Bahrami, Alina K. Moriarty, Paulo De Melo, W. Coles Keeter, Nada S. Alakhras, Andrew S. Nelson, Madeline Hoover, Maria S. Barrios, Jerry L. Nadler, C. Henrique Serezani, Mark H. Kaplan, Elena V. Galkina
Publikováno v:
JCI Insight, Vol 6, Iss 14 (2021)
Signal transducer and activator of transcription 4 (STAT4) is expressed in hematopoietic cells and plays a key role in the differentiation of T helper 1 cells. Although STAT4 is required for immunity to intracellular pathogens, the T cell–independe
Externí odkaz:
https://doaj.org/article/b83149859da34de388f9135a72903011
Publikováno v:
The Journal of Immunology. 210:359-368
Macrophages are sentinels of the innate immune system that maintain tissue homeostasis and contribute to inflammatory responses. Their broad scope of action depends on both functional heterogeneity and plasticity. Small noncoding RNAs called microRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d519e725f6f6625f083f4a4363358dcd
https://doi.org/10.4049/jimmunol.2200467
https://doi.org/10.4049/jimmunol.2200467