Zobrazeno 1 - 10
of 173
pro vyhledávání: '"C Hanrahan"'
Publikováno v:
South African Medical Journal, Vol 108, Iss 9, Pp 734-740 (2018)
Background. There is a growing interest in involving community health workers (CHWs) into the formal healthcare system in South Africa (SA).Objectives. To generate evidence for defining CHW tasks in urban SA.Methods. A cross-sectional survey of resid
Externí odkaz:
https://doaj.org/article/faa226ade0af4d35b55e23befe4aa24b
Autor:
Ashley N. Brown, Yinzhi Lang, Jieqiang Zhou, Evelyn J. Franco, Kaley C. Hanrahan, Juergen B. Bulitta, George L. Drusano
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has radically altered daily life. Effective antiviral therapies to combat COVID-19, especially severe disease, remain s
Externí odkaz:
https://doaj.org/article/1665716aa8544c81845004b58cd2f18b
Publikováno v:
Microorganisms, Vol 11, Iss 5, p 1342 (2023)
In a companion paper, we demonstrated that the nucleoside analogue favipiravir (FAV) suppressed Zika virus (ZIKV) replication in three human-derived cell lines—HeLa, SK-N-MC, and HUH-7. Our results revealed that FAV’s effect was most pronounced i
Externí odkaz:
https://doaj.org/article/576a101fbf99473088434f664b7e4348
Publikováno v:
Viruses, Vol 15, Iss 5, p 1175 (2023)
The host targeting antiviral, UV-4B, and the RNA polymerase inhibitor, molnupiravir, are two orally available, broad-spectrum antivirals that have demonstrated potent activity against SARS-CoV-2 as monotherapy. In this work, we evaluated the effectiv
Externí odkaz:
https://doaj.org/article/41f1430e0fe24cd3b17f00fa6ebc9198
Publikováno v:
Microorganisms, Vol 11, Iss 5, p 1097 (2023)
This study aims to evaluate the antiviral potential of the nucleoside analogue favipiravir (FAV) against ZIKV, an arbovirus for which there are no approved antiviral therapies, in three human-derived cell lines. HeLa (cervical), SK-N-MC (neuronal), a
Externí odkaz:
https://doaj.org/article/d6c3fd94706a41cfb06ea4ce861b3807
Autor:
Sharanbasappa S. Karade, Evelyn J. Franco, Ana C. Rojas, Kaley C. Hanrahan, Alexander Kolesnikov, Wenbo Yu, Alexander D. MacKerell, Daniel C. Hill, David J. Weber, Ashley N. Brown, Anthony M. Treston, Roy A. Mariuzza
Publikováno v:
Journal of Medicinal Chemistry. 66:2744-2760
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbf576683afdffe51f5660b95a96de1a
https://doi.org/10.1021/acs.jmedchem.2c01750
https://doi.org/10.1021/acs.jmedchem.2c01750
Publikováno v:
Viruses, Vol 13, Iss 3, p 415 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of novel coronavirus disease 2019 (COVID-19), has become a severe threat to global public health. There are currently no antiviral therapies approved for the treatment
Externí odkaz:
https://doaj.org/article/97237a2187e9457fa7a2ce57bc483560
Autor:
Evelyn J. Franco, Xun Tao, Kaley C. Hanrahan, Jieqiang Zhou, Jürgen B. Bulitta, Ashley N. Brown
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 307 (2021)
Chikungunya virus (CHIKV) is an alphavirus associated with a broad tissue tropism for which no antivirals or vaccines are approved. This study evaluated the antiviral potential of favipiravir (FAV), interferon-alpha (IFN), and ribavirin (RBV) against
Externí odkaz:
https://doaj.org/article/2f415b893df044c8a85e0b0c29312966
Autor:
K Kitt, C Hanrahan
Publikováno v:
Age and Ageing. 51
Background Hip fractures have long been associated with significant morbidity and mortality and threat to independent living. A major, treatable risk factor for the development of a hip fracture is osteoporosis. The objective of this study was to inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e46b3b48f50a39ca146fc47e6577cd2e
https://doi.org/10.1093/ageing/afac218.295
https://doi.org/10.1093/ageing/afac218.295
Publikováno v:
Age and Ageing. 51
Background Choosing if, and when antithrombotic therapy should be re-started after Intracerebral Haemorrhage (ICH) is a decision commonly faced by clinicians working in stroke medicine. In spite of this, there is a dearth of international guidelines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa4f20486ec60c9512e0dd0652ba9f1c
https://doi.org/10.1093/ageing/afac218.293
https://doi.org/10.1093/ageing/afac218.293