Zobrazeno 1 - 10
of 10
pro vyhledávání: '"C H Langeveld"'
Publikováno v:
Experimental Neurology. 117:196-203
Cyclic AMP is supposed to play a role in cell growth and differentiation via activation of protein kinase A. The cAMP signal transduction pathway may therefore be used as a target for the development of anticancer drugs. We compared the effects of 8C
Publikováno v:
Journal of Neuroscience Research. 31:524-531
Dexamethasone is frequently used in the therapy of brain tumor patients. We investigated the effect of dexamethasone on the proliferation of three short-term and four established human glioma cell lines in vitro, using a microculture tetrazolium assa
Autor:
A, Burdorf, Saskia M F, Pluijm, C H, Langeveld, Jozien M, Bensing, Lex M, Bouter, Paul J, van der Maas, Johan P, Mackenbach
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 153(7)
Publikováno v:
Journal of neuroscience research. 49(3)
We have successfully established highly enriched astrocyte cultures upon passaging of primary cultures derived from various regions of postmortem human adult brain and spinal cord. Tissues were collected at autopsies with relatively short postmortem
Publikováno v:
European journal of pharmacology. 329(2-3)
Astrocytes protect neurons against reactive oxygen species such as hydrogen peroxide, a capacity which reportedly is abolished following loss of the antioxidant glutathione. Anethole dithiolethione, a sulfur-containing compound which is used in human
Autor:
R, Lopez-Lopez, C H, Langeveld, P E, Pizao, R E, van Rijswijk, J, Wagstaff, H M, Pinedo, G J, Peters
Publikováno v:
Anti-cancer drug design. 9(4)
The trypanocidal drug, suramin, has been shown to possess antitumour activity, both in vitro and in vivo. Its mechanism of action, however, remains unclear although an effect on signal transduction has been proposed. We therefore studied the in vitro
Publikováno v:
Cancer research. 52(14)
8-Chloroadenosine 3':5'-monophosphate (8ClcAMP) inhibits the growth of human glioma cell lines at much lower concentrations than more commonly used cyclic AMP analogues, without inducing morphological differentiation. The mechanism by which 8ClcAMP e
Publikováno v:
Scopus-Elsevier
Publikováno v:
Neuro-Oncology ISBN: 9789401053907
Cyclic adenosine 3′,5′-monophosphate (cAMP) is a second messenger playing an important role in cell growth and differentiation [1]. Since cAMP itself hardly enters the cell, the role of cAMP has been demonstrated by the use of cAMP analogs such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ad68fad55ddcff3e8e9adefcb60ec5f
https://doi.org/10.1007/978-94-011-3152-0_40
https://doi.org/10.1007/978-94-011-3152-0_40
Publikováno v:
Experientia. 39(10)
Auricular chondrocytes isolated from 4-day-old rabbits and grown in vitro for 14 days, proliferated rapidly and produced a conspicuous network of elastic fibers. Beta-aminoproprionitrile (BAPN), which in vivo inhibits cross-linking of elastin, decrea