Zobrazeno 1 - 10
of 48
pro vyhledávání: '"C H Holmes"'
Autor:
Alyson Fisk, P. J. Toghill, E. B. Austin, P. G. Smith, C. H. Holmes, Barbara Gunn, C. J. Hawkey, M. J. Embleton, Robert W. Baldwin
Publikováno v:
Liver. 3:295-302
A monoclonal antibody, RL23/36, reacting preferentially with a determinant expressed on normal human hepatocytes is described. Use of an immunohistochemical technique on frozen sections from a range of 75 human liver biopsy specimens revealed that th
Publikováno v:
International Journal of STD & AIDS. 17:289-295
We quantitatively investigated inflammatory cells in the male urethra. Leukocytes in the first catch urine (FCU) from 87 men with and without urethritis were quantitated using haemocytometer counts and stained with an anti-CD45 pan-leukocyte antibody
Publikováno v:
Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture. 220:307-317
The research presented in this paper describes the use of a novel multidisciplinary design methodology. Various design methodologies are reviewed and evaluated in terms of their capability to be used for the effective design of a medical device. The
Publikováno v:
The Journal of Immunology. 164:319-328
HLA-F is currently the most enigmatic of the human MHC-encoded class Ib genes. We have investigated the expression of HLA-F using a specific Ab raised against a synthetic peptide corresponding to amino acids 61–84 in the α1 domain of the predicted
Publikováno v:
Immunology. 96:649-655
Human placental trophoblast is critically involved in mediating maternal tolerance of the fetal semiallograft. Genes encoding highly polymorphic major histocompatibility complex (MHC) class I and class II antigens that could provoke maternal immune r
Publikováno v:
Immunology. 93:437-445
Human placental trophoblast expresses as unusual repertoire of major histocompatibility complex (MHC) class I products that appears to reflect the unique role of this epithelium in mediating feto-maternal relations during pregnancy. Trophoblast is de
Publikováno v:
The Journal of Immunology. 154:5665-5674
The expression of HLA class I Ag by term human amnion epithelial cells was investigated. In immunostaining and FACS analysis, mAb to monomorphic class I Ag reacted extensively with amnion cells, whereas polymorphic mAb reactivity was more limited and
Autor:
K. L. Simpson, C. H. Holmes
Publikováno v:
Reproduction. 102:419-424
The seminal plasma complement regulator membrane cofactor protein (MCP) was examined by sequential centrifugation and phase separation in the detergent Triton X-114. The presence of MCP components in seminal plasma depleted of the 40 kDa sperm MCP pr
Autor:
K L Simpson, C H Holmes
Publikováno v:
Baillière's Clinical Obstetrics and Gynaecology. 6:439-460
Recent studies have revealed that human trophoblast expresses three membrane-bound proteins which function specifically to regulate the activity of complement. These proteins are already known to be widely distributed in normal adult tissues where th
Publikováno v:
The Journal of Immunology. 149:668-675
HLA class I Ag expression was investigated in the human fetal liver. By immunostaining, mAb to monomorphic class I Ag showed widespread reactivity with both epithelial and hemopoietic cells. By contrast, mAb to polymorphic determinants showed more re