Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes

Autor: L, Kappos, C H, Polman, M S, Freedman, G, Edan, H P, Hartung, D H, Miller, X, Montalban, F, Barkhof, L, Bauer, P, Jakobs, C, Pohl, R, Sandbrink

Publikováno v: Neurology. 67:1242-1249

To assess efficacy, safety, and tolerability of every-other-day interferon beta-1b treatment in patients with a first clinical event suggestive of multiple sclerosis (MS) (clinically isolated syndrome).We conducted a multicenter, randomized, double-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d21069dd824591e4bb2b31d9bca326
https://doi.org/10.1212/01.wnl.0000237641.33768.8d

Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration

Autor: H, Kearney, M A, Rocca, P, Valsasina, L, Balk, J, Sastre-Garriga, J, Reinhardt, S, Ruggieri, A, Rovira, C, Stippich, L, Kappos, T, Sprenger, P, Tortorella, M, Rovaris, C, Gasperini, X, Montalban, J J G, Geurts, C H, Polman, F, Barkhof, M, Filippi, D R, Altmann, O, Ciccarelli, D H, Miller, D T, Chard

Publikováno v: Kearney, H, Rocca, M A, Valsasina, P, Balk, L, Sastre-Garriga, J, Reinhardt, J, Ruggieri, S, Rovira, A, Stippich, C, Kappos, L, Sprenger, T, Tortorella, P, Rovaris, M, Gasperini, C, Montalban, X, Geurts, J J G, Polman, C H, Barkhof, F, Filippi, M, Altmann, D R, Ciccarelli, O, Miller, D H & Chard, D T 2014, ' Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration ', Multiple Sclerosis, vol. 20, no. 1, pp. 72-80 . https://doi.org/10.1177/1352458513492245
Multiple Sclerosis, 20(1), 72-80. SAGE Publications Ltd
Multiple Sclerosis (Houndmills, Basingstoke, England)

Background: Understanding long-term disability in multiple sclerosis (MS) is a key goal of research; it is relevant to how we monitor and treat the disease. Objectives: The Magnetic Imaging in MS (MAGNIMS) collaborative group sought to determine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0d85348c235dd758269809de9adf0384
https://research.vumc.nl/en/publications/f6dab389-937b-4fb3-8bd3-e270c998ab8a

Regular review: Drug treatment of multiple sclerosis

Autor: C H Polman, B M J Uitdehaag

Publikováno v: BMJ. 321:490-494

BMJ 2000;321:490-4 Multiple sclerosis is the most common cause of chronic neurological disability in young adults, with a prevalence of about 1 in 1000. About 50% of patients are unable to walk without assistance 15 years after onset As yet, no treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f90f26c43f4dfdc9237b9b8b6f226a6b
https://doi.org/10.1136/bmj.321.7259.490

EFNS guidelines on diagnosis and management of neuromyelitis optica

Autor: J, Sellner, M, Boggild, M, Clanet, R Q, Hintzen, Z, Illes, X, Montalban, R A, Du Pasquier, C H, Polman, P S, Sorensen, B, Hemmer

Publikováno v: European journal of neurology. 17(8)

Neuromyelitis optica (NMO) or Devic's disease is a rare inflammatory and demyelinating autoimmune disorder of the central nervous system (CNS) characterized by recurrent attacks of optic neuritis (ON) and longitudinally extensive transverse myelitis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::77c08bf6bcfd9bc7a3d17381a04861fd
https://pubmed.ncbi.nlm.nih.gov/20528913

Anti‐myelin antibodies in multiple sclerosis: clinically useful?

Autor: J Killestein, C H Polman

To investigate whether the presence of serum antibodies against myelin oligodendrocyte glycoprotein (MOG) and myelin basic protein (MBP) in patients with a clinically isolated syndrome (CIS) predicts the interval to develop more frequently and earlie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc515c11739e640bf53d4c0c19f70895
https://europepmc.org/articles/PMC2077472/