Zobrazeno 1 - 10
of 59
pro vyhledávání: '"C H, Barton"'
Autor:
S Elizabeth von Biberstein, Andrew C H Barton, Robert Shakar, Paul F Kamitsuka, Pamela W Firetti, Hollis M Ray, J West Paul, Kevin M McNabb, Andrew L Almeter
Publikováno v:
American journal of medical quality : the official journal of the American College of Medical Quality. 37(1)
Resuming elective surgery amid shortages of rapid severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tests and personal protective equipment, while protecting patient and staff safety, posed a challenge at the study institution. Many hospit
Autor:
Thelma Biggs, C. H. Barton, Holly Bowen, V. H. Perry, Derek A. Mann, S. T. Baker, E.S. Phillips
Publikováno v:
Biochemical Society Transactions. 30:774-777
The Nrampl (natural resistance-associated macrophage protein 1) gene modulates the growth of intracellular pathogens and encodes a divalent cation transporter within lysosomes/late endosomes of macrophages. Nrampl modulates the cytoplasmic iron pool.
Publikováno v:
Journal of Leukocyte Biology. 67:501-507
Nramp 1 (natural resistance-associated macrophage protein) controls resistance to infection by intracellular pathogens in mice. Nramp 1 regulates the microenvironment of the invading pathogen by increasing the luminal iron that participates in the Ha
Nrampl: a link between intracellular iron transport and innate resistance to intracellular pathogens
Publikováno v:
Journal of Leukocyte Biology. 66:757-762
Nramp1 (natural resistance-associated macrophage protein one) regulates intracellular pathogen proliferation and macrophage inflammatory responses. Murine Nramp1 exhibits a natural polymorphism with alleles termed resistant and susceptible. Alleles r
Publikováno v:
AIDS. 13:1443-1452
Objectives: There is now a strong consensus that the neurotoxic properties of HIV-1 are likely to be mediated by an indirect mechanism in which neurones are damaged by infected mononuclear cells. The aim of this study was to determine the ability of
Publikováno v:
Journal of Molecular Biology. 290:21-35
Human immunodeficiency virus type 1 (HIV-1) Nef is important for viral infectivity and pathogenicity. HIV-1 infection is associated with inappropriate activation and defects in the function of monocytes/macrophages. We have studied the effects of HIV
Publikováno v:
Journal of General Virology. 77:1643-1647
Human immunodeficiency virus type 1 (HIV-1) infection is frequently associated with concurrent infection by opportunistic pathogens, against which production of nitric oxide by host macrophages provides a first line of defence. We have investigated w
Publikováno v:
Biochemical Society Transactions. 32:1084-1086
Slc11a1/Nramp1 (solute carrier family 11 member a1/murine natural resistance-associated macrophage protein 1 gene) encodes a divalent cation transporter that resides within lysosomes/late endosomes of macrophages. Nramp1 modulates the cellular distri
Publikováno v:
Molecular Medicine. 1:267-279
BACKGROUND: The Ity/Lsh/Bcg gene on mouse chromosome 1 regulates priming/activation of macrophages for antimicrobial and tumouricidal activity. A candidate gene expressed in macrophages has been identified by positional cloning and full-length sequen
Autor:
Jacqueline K. White, C. H. Barton, Jenefer M. Blackwell, A.-M. Baker, S. Searle, H. Williams, Marie-Anne Shaw
Publikováno v:
Molecular Medicine. 1:194-205
Murine Nramp is a candidate for the macrophage resistance gene Ity/Lsh/Bcg. Sequence analysis of human NRAMP was undertaken to determine its role in man. A yeast artificial chromosome carrying NRAMP was subcloned and positive clones sequenced. The tr