Zobrazeno 1 - 10
of 2 401
pro vyhledávání: '"C Griffiths"'
Autor:
Tomas Malinauskas, Gareth Moore, Amalie F. Rudolf, Holly Eggington, Hayley L. Belnoue-Davis, Kamel El Omari, Samuel C. Griffiths, Rachel E. Woolley, Ramona Duman, Armin Wagner, Simon J. Leedham, Clair Baldock, Hilary L. Ashe, Christian Siebold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Twisted gastrulation (TWSG1) is an evolutionarily conserved secreted glycoprotein which controls signaling by Bone Morphogenetic Proteins (BMPs). TWSG1 binds BMPs and their antagonist Chordin to control BMP signaling during embryonic develop
Externí odkaz:
https://doaj.org/article/ddfaa798787944ee8ae8169dabd72ec6
Autor:
Samuel C Griffiths, Jia Tan, Armin Wagner, Levi L Blazer, Jarrett J Adams, Srisathya Srinivasan, Shayan Moghisaei, Sachdev S Sidhu, Christian Siebold, Hsin-Yi Henry Ho
Publikováno v:
eLife, Vol 13 (2024)
The receptor tyrosine kinase ROR2 mediates noncanonical WNT5A signaling to orchestrate tissue morphogenetic processes, and dysfunction of the pathway causes Robinow syndrome, brachydactyly B, and metastatic diseases. The domain(s) and mechanisms requ
Externí odkaz:
https://doaj.org/article/439dab7e296646b59ddc2e91b98ed24d
Autor:
Rong Li, Ningyan Zhang, Zhiqiang An, Wei Xiong, Huai-Chin Chiang, Hui Deng, Junquan Liu, Victor Laurent, Samuel C Griffiths, Jasmin Dülfer, Xiujie Sun, Y Whitney Yin, Wenliang Li, Laurent P Audoly, Thomas Schürpf
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background Immune exclusion (IE) where tumors deter the infiltration of immune cells into the tumor microenvironment has emerged as a key mechanism underlying immunotherapy resistance. We recently reported a novel role of discoidin domain-containing
Externí odkaz:
https://doaj.org/article/3537ca4000574c579032deb0a579a11b
Autor:
Samuel C. Griffiths, Rebekka A. Schwab, Kamel El Omari, Benjamin Bishop, Ellen J. Iverson, Tomas Malinauskas, Ramin Dubey, Mingxing Qian, Douglas F. Covey, Robert J. C. Gilbert, Rajat Rohatgi, Christian Siebold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Hedgehog-Interacting Protein (HHIP) is the only reported secreted inhibitor of Sonic Hedgehog (SHH) signalling. Here, the authors report structures of the HHIP N- and C-terminal domains, both in complexes with glycosaminoglycans, providing insights i
Externí odkaz:
https://doaj.org/article/420c08df587c4e738a4706dedda2d860
Autor:
M. Burman, A. Copas, D. Zenner, V. Hickson, L. Gosce, D. Trathen, R. Ashcroft, A. R. Martineau, I. Abubakar, C. Griffiths, H. Kunst
Publikováno v:
BMC Public Health, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background The identification and treatment of LTBI is a key component of the WHO’s strategy to eliminate TB. Recent migrants from high TB-incidence countries are recognised to be at risk TB reactivation, and many high-income countries hav
Externí odkaz:
https://doaj.org/article/b4b9378fff704df28d9d1d4b522c5e07
Autor:
Louise Newton, Amy M. DeLozier, Philip C. Griffiths, Jennifer N. Hill, Stacie Hudgens, Tara Symonds, Jonathon C. Gable, Jim Paik, Kathleen W. Wyrwich, Lawrence F. Eichenfield, Linda Abetz-Webb, Jonathan I. Silverberg
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 3, Iss 1, Pp 1-12 (2019)
Abstract Background Atopic dermatitis (AD) is a common skin disorder characterized by chronic inflammation, altered skin barrier function, and inflammatory cell skin infiltration that decreases health-related quality of life (HRQoL). The study object
Externí odkaz:
https://doaj.org/article/32d1a2b495074b8f9ac3f17e1f886d0a
Autor:
Constance A. Mitchell, Joseph T. Dever, Stefan Gafner, James C. Griffiths, Daniel S. Marsman, Cynthia Rider, Cara Welch, Michelle R. Embry
Publikováno v:
Zeitschrift für Phytotherapie. 44:21-29
ZusammenfassungDie Verwendung von pflanzlichen Heilmitteln und Nahrungsergänzungsmitteln ist weit verbreitet. In vielen Ländern der Welt weisen die Verkaufszahlen auf eine steigende Beliebtheit dieser Produkte hin. Daher ist die Gewährleistung der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e5ed122b1785d8ccba1e043591b1369
https://doi.org/10.1055/a-1773-4122
https://doi.org/10.1055/a-1773-4122
Autor:
M Carpenter, C Griffiths
Publikováno v:
African Journal of Marine Science. 45:51-56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7dfb4b63316c22c67a20d717e600500
https://doi.org/10.2989/1814232x.2022.2158131
https://doi.org/10.2989/1814232x.2022.2158131
Autor:
Jonathan W. Nelson, David I. Ortiz-Melo, Natalie K. Mattocks, Jacqueline M. Emathinger, Jessica Prescott, Katherine Xu, Robert C. Griffiths, Rumie Wakasaki, Paul D. Piehowski, Michael P. Hutchens, Thomas M. Coffman, Susan B. Gurley
Publikováno v:
Kidney360
BACKGROUND: ACE2 is a key enzyme in the renin-angiotensin system (RAS) capable of balancing the RAS by metabolizing angiotensin II (AngII). First described in cardiac tissue, abundance of ACE2 is highest in the kidney, and it is also expressed in sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b439da9c86ad6af99a218de45a6160b6
https://doi.org/10.34067/kid.0001622022
https://doi.org/10.34067/kid.0001622022
Autor:
Kremlin Wickramasinghe, John C. Mathers, Suzan Wopereis, Daniel S. Marsman, James C. Griffiths
Publikováno v:
Journal of Nutritional Science, Vol 9 (2020)
Across the globe, there has been a marked increase in longevity, but significant inequalities remain. These are exacerbated by inadequate access to proper nutrition and health care services and to reliable information to make the decisions related to
Externí odkaz:
https://doaj.org/article/f383e0dc6b9948b9a3117494b780dd32