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of 510
pro vyhledávání: '"C Gespach"'
Autor:
Nicole Porchet, B Gosselin, C Gespach, Tor C. Savidge, Jean-Pierre Aubert, Marie-Pierre Buisine, L Devisme
Publikováno v:
Gut. 43:519-524
Background—The intestinal epithelium is covered by a continuous layer of mucus which is secreted by well differentiated epithelial cells. Disregulation of the expression of mucins has been reported to have possible implications in the neoplastic pr
Autor:
Y, Mahida, S, Djelloul, A, Atfi, C, Ciacci, M, Debeaumont, S, Chevalier, C, Gespach, D, Podolsky
Publikováno v:
International journal of oncology. 9(2)
A new continuous cell line designated ESKI-1 was established by transfection of rat fetal intestinal epithelial cells with ecotropic retroviruses containing SV40 large T oncogene. The ESKI-1 cell line exhibits morphologic features of an epithelial ce
Autor:
P-O, Lafontaine, M, Arnal, N, Buron, E, Solary, S, Lizard, A, Bron, J, Bara, C, Gespach, C, Creuzot-Garcher
Publikováno v:
Journal francais d'ophtalmologie. 26(10)
Trefoil factor family (TFF) peptides (formerly P-domain peptides; trefoil factor) are small (7-12 kDa) protease-resistant secreted peptides designated pS2 (or TFF1), SP (TFF2) and ITF (TFF3). Human conjunctival goblet cells (GCs) are known to synthes
Publikováno v:
Bulletin du cancer.
Therapeutic innovation in oncology often requires the optimization of combinations with active drugs based on in vitro and in vivo data. This is exemplified by oxaliplatin for which several preclinical studies of combinations have been realized. Oxal
Publikováno v:
Molecular pharmacology. 60(2)
It was shown previously that platelet-activating factor receptors (PAF-Rs) inhibit invasiveness of colonic and kidney epithelial cells induced by the src and Met oncogenes via a pertussis toxin-sensitive mechanism. Therefore, Madin-Darby canine kidne
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Publikováno v:
Cancer research. 60(3)
Bile acids were shown previously to inhibit proliferation and to induce monocytic differentiation in HL60 human acute promyelocytic leukemia cells (A. Zimber et al., Int. J. Cancer, 59: 71-77, 1994). In this report, we hypothesized that bile acids ma
Publikováno v:
Biochemical Society symposium. 65
The E-cadherin-catenin complex is pivotal for the regulation of cancer invasion. It not only serves cell-cell adhesion but also transduces signals from the micro-environment to other molecular complexes possibly implicated in invasion. Both functions
Autor:
T, André, E, Chastre, L, Kotelevets, J C, Vaillant, C, Louvet, J, Balosso, E, Le Gall, S, Prévot, C, Gespach
Publikováno v:
La Revue de medecine interne. 19(12)
Angiogenesis activation plays a crucial role in tumoral growth and metastases dissemination. This review summarizes and analyzes current knowledge on molecular mechanisms related to angiogenesis and the prognostic value of its effectors. It also focu