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of 259
pro vyhledávání: '"C Gause"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102208- (2023)
Summary: Preserving structurally intact tissue through proper tissue fixation and cryopreservation minimizes tissue autolysis, desiccation, and enzymatic degradation. In this protocol, we describe the use of an optimized fresh freezing technique that
Externí odkaz:
https://doaj.org/article/b37180648bee49c8be0c9e4ec08c0659
Autor:
Eliezer Rovira-Diaz, Darine W. El-Naccache, Jojo Reyes, Yanlin Zhao, Azadeh Nasuhidehnavi, Fei Chen, William C. Gause, George S. Yap
Publikováno v:
The Journal of Immunology. 209:2160-2171
More than 2 billion people worldwide are infected with helminths. Thus, it is possible for individuals to experience concomitant infection with helminth and intracellular microbes. Although the helminth-induced type 2 response can suppress type 1 pro
Autor:
Marianna Lovászi, Zoltán H. Németh, Pál Pacher, William C. Gause, Gebhard Wagener, György Haskó
Publikováno v:
Purinergic Signalling. 18:345-358
Autor:
Raymond B. Birge, Thomas E. Spires, Michael Quigley, William C. Gause, Pankaj K. Mishra, Tessa Bergsbaken, Sergei V. Kotenko, Mariana S. De Lorenzo, Chan Gao, Michael Wichroski, Yun-juan Chang, Kevin C. Lahey, Canan Kasikara, Varsha Gadiyar, Dhriti Mehta, David Calianese, Ke Geng, Sushil Kumar, Viralkumar Davra
Figure S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c022c8f5090104975241f11d235eae
https://doi.org/10.1158/0008-5472.22427005
https://doi.org/10.1158/0008-5472.22427005
Autor:
Nuriban, Valero-Pacheco, Eric K, Tang, Noura, Massri, Rachel, Loia, Anat, Chemerinski, Tracy, Wu, Salma, Begum, Darine W, El-Naccache, William C, Gause, Ripla, Arora, Nataki C, Douglas, Aimee M, Beaulieu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(35)
The pregnant uterus is an immunologically rich organ, with dynamic changes in the inflammatory milieu and immune cell function underlying key stages of pregnancy. Recent studies have implicated dysregulated expression of the interleukin-1 (IL-1) fami
Autor:
Fei Chen, Wenhui Wu, Lianhua Jin, Ariel Millman, Mark Palma, Darine W. El-Naccache, Katherine E. Lothstein, Chen Dong, Karen L. Edelblum, William C. Gause
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2775-2783.e3 (2018)
Summary: Emphysema results in destruction of alveolar walls and enlargement of lung airspaces and has been shown to develop during helminth infections through IL-4R-independent mechanisms. We examined whether interleukin 17A (IL-17A) may instead modu
Externí odkaz:
https://doaj.org/article/cf63e538e07840a19c499fb5d348147a
Autor:
George S. Yap, William C. Gause
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Helminths are ubiquitous and have chronically infected vertebrates throughout their evolution. As such helminths have likely exerted considerable selection pressure on our immune systems. The large size of multicellular helminths and their limited re
Externí odkaz:
https://doaj.org/article/3be9ad864ee54222bc9bbd9210a8d2b2
Autor:
Katherine E. Lothstein, Fei Chen, Pankaj Mishra, Danielle J. Smyth, Wenhui Wu, Alexander Lemenze, Yosuke Kumamoto, Rick M. Maizels, William C. Gause
Intestinal helminth parasites express excretory/secretory (ES) molecules, which modulate the type-2 immune response including anti-inflammatory and tissue repair pathways. TGF-β mimic (TGM), an ES molecule secreted by Heligmosomoides polygyrus (Hp),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9650096830355b3299c2ba326e90f638
https://doi.org/10.1101/2022.09.24.509317
https://doi.org/10.1101/2022.09.24.509317
Akademický článek
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Publikováno v:
Trends Immunol
Type 2 immune responses are typically associated with protection against helminth infections and also with harmful inflammation in response to allergens. Recent advances have revealed that type 2 immunity also contributes to sterile inflammation, can