Zobrazeno 1 - 10
of 54
pro vyhledávání: '"C G Hanratty"'
Autor:
Lana J. Dixon, G. Dennis Johnston, Lawrence T. McGrath, Naglaa A. El-Sherbeeny, Paul Hamilton, William J. Leahey, C G Hanratty, David R. Morgan, Gary E. McVeigh
Publikováno v:
The American Journal of Cardiology. 97:547-551
We investigated the effects of omega-3 fatty acids administration on endothelium-dependent vasodilation in patients > or =65 years old who received treatment for chronic heart failure (CHF). Twenty patients (mean age 73 years; 15 men) with grade II a
Autor:
Ronan Donnelly, Michael P. Frenneaux, M Riley, C O'Dochartaigh, Hean Ong, Ian S. Young, C G Hanratty, S. L. Lovell, Paul Nicholls
Publikováno v:
Clinical Science. 106:413-419
Elevated blood levels of Hcy (homocysteine) are associated with endothelial dysfunction in the systemic and coronary arterial beds. We wished to know if similar changes could be detected in the pulmonary circulation, using non-invasive tests. We stud
Autor:
Gary E. McVeigh, Bernard Silke, Lana J. Dixon, C G Hanratty, Douglas R. Morgan, Patrick Allen
Publikováno v:
European Journal of Clinical Pharmacology. 59:195-199
To evaluate the effects of the intravenous administration of the nitric oxide synthesis inhibitor N(g)nitro-L-arginine methyl ester (L-NAME) in healthy volunteers.L-NAME (0.25, 0.5 and 0.75 mg/kg over 8 min) was infused in 13 healthy male volunteers.
Autor:
Adrian Devine, C G Hanratty, Lawrence T. McGrath, David G.A. Morgan, Lana J. Dixon, Martin Wilson, Gary E. McVeigh, Paul Hamilton, William J. Leahey
Publikováno v:
Circulation. 106:208-213
Background — The therapeutic benefits that accompany the continuous administration of organic nitrates are attenuated by the development of tolerance to the compounds. Altered superoxide production and NO bioavailability have been implicated in con
Publikováno v:
Europace. 4:281-287
The embryological development of the superior vena cava (SVC) is complex. If the left common cardinal vein fails to occlude it can, along with the left duct of Cuvier form a left SVC, which frequently drains into the coronary sinus. This may result i
Publikováno v:
Heart. 85:326-330
BACKGROUND—Raised homocysteine is a risk factor for vascular disease. Homocysteine is formed from methionine, and dietary manipulation of homocysteine in primates and humans with oral methionine is associated with endothelial dysfunction. A cause-e
Vasoconstriction to Endothelin-1 is Blunted in Non-Insulin-Dependent Diabetes: A Dose-Response Study
Publikováno v:
Journal of Cardiovascular Pharmacology. 36:203-208
The haemodynamic hypothesis for the pathogenesis of diabetic microangiopathy argues that an initial increase in microvascular blood flow leads to microvascular sclerosis and disturbed autoregulation. Endothelin-1 (ET-1) is an endothelium-derived vaso
Publikováno v:
Journal of Cardiovascular Pharmacology. 33:859-867
Full antagonists of the cardiac beta-adrenoceptor improve heart-rate variability (HRV) in humans; however, partial agonism at the beta2-adrenoceptor has been suggested to decrease HRV. We therefore studied the HRV effects of some partial agonists of
Publikováno v:
British Journal of Clinical Pharmacology. 47:157-166
AIMS To examine the impact on heart rate variability (HRV), of agonism or antagonism at the cardiac beta2-adrenoceptor in healthy volunteers, using standard time-domain summary statistics and non-linear methods (scatterplot and quadrant analysis). ME
Publikováno v:
Coronary Artery Disease. 10:633-640
Left ventricular hypertrophy (LVH) is an important independent risk factor for cardiovascular disease and is associated with an increased risk of ventricular dysrhythmia, coronary artery disease, myocardial infarction, stroke, heart failure and perip