Zobrazeno 1 - 7
of 7
pro vyhledávání: '"C G Cockburn"'
Publikováno v:
Thrombosis and Haemostasis. 61:378-385
SummaryThe binding of fn to collagen (type I) fibres has been found to resemble that of vWf in the following respects: 1. Binding is rapid, specific, saturable, similar at 4 and 37°C, and reduced by increasing ionic strength.2. Binding is not inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8cde201eb35983d9cd78eaadb8dbf7a
https://doi.org/10.1055/s-0038-1646600
https://doi.org/10.1055/s-0038-1646600
Publikováno v:
Thrombosis and Haemostasis. 40:302-315
SummaryHighly purified factor VIII was incubated for up to 24 hours in the presence of plasmin, and the biological activities and peptide structure of the digestion products determined at intervals. Procoagulant activity (VIIIC) was rapidly lost, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ecfbbc07312762e5bd0d10acc458c7
https://doi.org/10.1055/s-0038-1648664
https://doi.org/10.1055/s-0038-1648664
Publikováno v:
Thrombosis and Haemostasis. 59:186-192
SummaryFollowing fragmentation of the collagen molecule, we have examined the ability of the isolated fragments to bind vWf. In view of the importance of collagen tertiary and quaternary structure for binding, fragments were first renatured to restor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fbf7cbd5bc0493f176978b22f9140a0
https://doi.org/10.1055/s-0038-1642751
https://doi.org/10.1055/s-0038-1642751
Autor:
C. G. Cockburn
Publikováno v:
VIth International Congress on Thrombosis and Haemostasis.
A dilute solution of highly purified human FVIII was cross-linked by dimethyl suberimidate (negligible intermolecular cross-linking), incubated in 0.2m mercaptoethanol for 35 min. At 37 c, and eluted through a sepharose 4b column. Unreduced SDS-polya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5d532f2d5347cc852a18739956fc047
https://doi.org/10.1055/s-0039-1680431
https://doi.org/10.1055/s-0039-1680431
Publikováno v:
Thrombosis and haemostasis. 40(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2949bde7a0183b344896f55085c98f8
https://pubmed.ncbi.nlm.nih.gov/153594
https://pubmed.ncbi.nlm.nih.gov/153594
Publikováno v:
Thrombosis and haemostasis. 59(2)
Following fragmentation of the collagen molecule, we have examined the ability of the isolated fragments to bind vWf. In view of the importance of collagen tertiary and quaternary structure for binding, fragments were first renatured to restore tripl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d754d25b6cf156907bde97b36415e98f
https://pubmed.ncbi.nlm.nih.gov/3260414
https://pubmed.ncbi.nlm.nih.gov/3260414
Publikováno v:
VIth International Congress on Thrombosis and Haemostasis.
Purified human factor VIII was incubated for up to 24 hours with plasmin, and the activity of the breakdown products studied at intervals. Factor VIII coagulant activity was lost within the first hour, but von Willebrand factor activity (FVIIIR:WF) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c1bc0d00fd3db1c8ca475167fe37796
https://doi.org/10.1055/s-0039-1680509
https://doi.org/10.1055/s-0039-1680509