Zobrazeno 1 - 10
of 12
pro vyhledávání: '"C G, Proud"'
Autor:
C G, Proud
Publikováno v:
Current topics in microbiology and immunology. 279
Protein synthesis requires nutrients both as precursors (amino acids) and as a source of energy, since this process consumes a high proportion of cellular metabolic energy. Recent work has shown that both types of nutrients directly influence the act
Autor:
C G, Proud
Publikováno v:
Progress in molecular and subcellular biology. 26
Publikováno v:
Journal of neurochemistry. 78(4)
Mice were subjected to 60 min occlusion of the left middle cerebral artery (MCA) followed by 1-6 h of reperfusion. Tissue samples were taken from the MCA territory of both hemispheres to analyse ischaemia-induced changes in the phosphorylation of the
Publikováno v:
The Biochemical journal. 358(Pt 2)
The eukaryotic initiation factor 4E (eIF4E) binding protein (4E-BP1) interacts directly with eIF4E and prevents it from forming initiation factor (eIF4F) complexes required for the initiation of cap-dependent mRNA translation. Insulin and other agent
Publikováno v:
The Journal of biological chemistry. 276(35)
The alpha(1)-adrenergic agonist phenylephrine (PE) and insulin each stimulate protein synthesis in cardiomyocytes. Activation of protein synthesis by PE is involved in the development of cardiac hypertrophy. One component involved here is p70 S6 kina
Publikováno v:
The Biochemical journal.
Eukaryotic initiation factor eIF2B and eukaryotic elongation factor eEF2 each mediate regulatory steps important for the overall regulation of mRNA translation in mammalian cells and are activated by insulin. Here, we demonstrate that their activatio
Publikováno v:
The Journal of biological chemistry. 271(29)
A cDNA from rat skeletal muscle encoding calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase (eEF-2K) has been cloned and sequenced, and the amino acid sequence of the protein has been deduced. The kinase is composed of 724 amino acids
Autor:
C G, Proud
Publikováno v:
Trends in biochemical sciences. 21(5)
The S6 ribosomal protein is phosphorylated by p70 S6 kinase (p70S6k). Although the cellular role of S6 phosphorylation is still not fully clear, studies on p70S6k and its activation have revealed the existence of a novel signalling pathway, clues to
Autor:
A, Flynn, C G, Proud
Publikováno v:
Cancer surveys. 27
Translational control has a key role in regulating cell growth. The mRNA binding translation factors (eIF4s) selectively modulate the translation of different mRNAs based on their differing properties, especially the extent of inhibitory secondary st
Publikováno v:
Biochemical Journal. 373:999-999