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Abstract 523: Sodium Nitrite Therapy Augments Ischemia-Induced Neovascularization and Blood Flow Recovery in Different Models of Hypertension

Autor: Ali Amin, Sookyoung Choi, Y Osman-Elazeik, N Badr El-Din, C G Kevil, G L Navar, P Kadowitz, M Trebak, Khalid Matrougui

Publikováno v: Hypertension. 60

Background: Arterial hypertension is a major risk factor that can lead to exacerbation of peripheral vascular disease due, in part, to endothelial dysfunction. Because sodium nitrite (SN) can be converted to nitric oxide (NO), which counteracts endot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b890d20be0aa6700061987ad15c6752
https://doi.org/10.1161/hyp.60.suppl_1.a523

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In vitro culture and characterization of gene targeted mouse endothelium

Autor: C G, Kevil, D C, Bullard

Publikováno v: Acta physiologica Scandinavica. 173(1)

Endothelial cells play a crucial role in maintaining cardiovascular homeostasis. Although many cardiovascular disorders involve endothelial cell dysfunction, the specific cellular and molecular mechanisms involved are not well known. We sought to est

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ef8aa36cabff1567face73fb1eb7027a
https://pubmed.ncbi.nlm.nih.gov/11678738

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Inflammatory mediators induce sequestration of VE-cadherin in cultured human endothelial cells

Autor: J S, Alexander, B C, Alexander, L A, Eppihimer, N, Goodyear, R, Haque, C P, Davis, T J, Kalogeris, D L, Carden, Y N, Zhu, C G, Kevil

Publikováno v: Inflammation. 24(2)

The mechanisms through which inflammatory mediators modify endothelial junctional structure are not well understood. Endothelial cells exposed to 1 mM H2O2, 0.1 mM histamine or 4 mM EDTA displayed decreased amounts of VE-cadherin on the cell surface

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7cfd45bb05f1d0c65f349f7be27773f7
https://pubmed.ncbi.nlm.nih.gov/10718113

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Activated T-lymphocytes express occludin, a component of tight junctions

Autor: J S, Alexander, T, Dayton, C, Davis, S, Hill, T H, Jackson, O, Blaschuk, M, Symonds, N, Okayama, C G, Kevil, F S, Laroux, S M, Berney, D, Kimpel

Publikováno v: Inflammation. 22(6)

T-lymphocytes routinely traffic from the lymphoid and vascular compartments to the tissues during immune surveillance and inflammatory responses. This egress occurs without compromising endothelial barrier, which is maintained by tight junctions (zon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bda101bed33f1c64c8a6550ffd91ff5
https://pubmed.ncbi.nlm.nih.gov/9824772

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Expression of zonula occludens and adherens junctional proteins in human venous and arterial endothelial cells: role of occludin in endothelial solute barriers

Autor: C G, Kevil, N, Okayama, S D, Trocha, T J, Kalogeris, L L, Coe, R D, Specian, C P, Davis, J S, Alexander

Publikováno v: Microcirculation (New York, N.Y. : 1994). 5(2-3)

The purpose of this study was to correlate the expression of occludin and VE-cadherin with the solute barrier properties of arterial and venous endothelial monolayers.Immunofluorescent confocal and traditional microscopy were used to determine juncti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e914b190350446979f8648ee695eb8d
https://pubmed.ncbi.nlm.nih.gov/9789260

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Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis

Autor: C G, Kevil, A, De Benedetti, D K, Payne, L L, Coe, F S, Laroux, J S, Alexander

Publikováno v: International journal of cancer. 65(6)

Studies aimed at elucidating the function of the protein synthesis factor eukaryotic initiation factor 4E (elF-4E) have demonstrated that overexpression of this protein results in marked cell phenotypic and proliferative changes, including neoplastic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a39fac265f4e8abd192deda2d63776ed
https://pubmed.ncbi.nlm.nih.gov/8631593

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Ten-Year Process Gas Turbine Experience

Autor: C. G. Kevil, J. G. Drost

Publikováno v: ASME 1969 Gas Turbine Conference and Products Show.

The Columbian Carbon Company Petrochemical Plant, formerly known as PCI or Petroleum Chemicals, Inc., has now operated three 13,000-hp class gas turbines for ten years. This paper reviews the overall plant arrangement and application of the units. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aead440eeb970e8751615976f6ece223
https://doi.org/10.1115/69-gt-56

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