Výsledky vyhledávání - "C G, Goodyer"

Pregnant Women's perceptions of exposure to brominated flame retardants

Autor: A. Lane, C. G. Goodyer, Justin M. Ashley, F. Rab, Alexandra Hodgson, Jeff Nisker, Sapna Sharma

Publikováno v: Paediatrics Publications
Reproductive Health

Background: Recent media reports on human studies associating brominated flame retardants (BFRs) in household products in pregnancy with urogenital anomalies in boys and endocrine disruption in both sexes. We sought to explore the perceptions of preg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6054f01be7a7ed9847a5588ffaa6773
https://ir.lib.uwo.ca/context/paedpub/article/3373/viewcontent/s12978_016_0257_2.pdf

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Developmental upregulation of human parathyroid hormone (PTH)/PTH-related peptide receptor gene expression from conserved and human-specific promoters

Autor: John H. White, Geoffrey N. Hendy, M. Minagawa, L C Alpert, J. D. Bettoun, David Goltzman, C G Goodyer

Publikováno v: Journal of Clinical Investigation. 102:958-967

The parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor (PTHR) functions in skeletal development and mediates an array of other physiological responses modulated by PTH and PTHrP. PTHR gene transcription in mouse is controlled by two promo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4521a1dcc82c6a9a57f390dd70d3a4
https://doi.org/10.1172/jci3678

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Human growth hormone receptor (GHR) expression in obesity: II. Regulation of the human GHR gene by obesity-related factors

Autor: Martin Wabitsch, C G Goodyer, Aysegul Erman

Publikováno v: International journal of obesity (2005). 35(12)

In our previous analyses, we found significantly lower levels of growth hormone receptor (GHR) mRNA in adipose tissues of obese than in those of lean individuals, suggesting that idiopathic obesity involves GH resistance due to decreased GHR availabi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d3bce696d551ccdb141754c46aa828
https://pubmed.ncbi.nlm.nih.gov/21386799

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Human growth hormone receptor (GHR) expression in obesity: I. GHR mRNA expression in omental and subcutaneous adipose tissues of obese women

Autor: Aysegul Erman, C G Goodyer, Alain Veilleux, André Tchernof

Publikováno v: International journal of obesity (2005). 35(12)

Growth hormone (GH)-deficient individuals display increased adiposity that can be effectively reduced by GH therapy because of GH's lipolytic effects. However, similar GH treatments of individuals with idiopathic obesity (not associated with an endoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c55c6fc95f8cd2e60e4e365b7e54da
https://pubmed.ncbi.nlm.nih.gov/21386804

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SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas

Autor: A Waha, A Koch, W Hartmann, U Milde, J Felsberg, A Hübner, T Mikeska, C G Goodyer, N Sörensen, I Lindberg, O D Wiestler, T Pietsch

Publikováno v: Oncogene. 26(38)

In a genome-wide screen using differential methylation hybridization (DMH), we have identified a CpG island within the 5' region and untranslated first exon of the secretory granule neuroendocrine protein 1 gene (SGNE1/7B2) that showed hypermethylati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891830cb23c23381674ca812d91ef6e3
https://pubmed.ncbi.nlm.nih.gov/17334394

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No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours

Autor: A, Koch, A, Waha, W, Hartmann, U, Milde, C G, Goodyer, N, Sörensen, F, Berthold, B, Digon-Söntgerath, J, Krätzschmar, O D, Wiestler, T, Pietsch

Publikováno v: Neuropathology and applied neurobiology. 30(5)

The sonic hedgehog (Shh) and the Wnt signalling pathways are involved in the development of medulloblastomas (MBs), the most frequent malignant brain tumours in children. Components of these two developmental and cancer-associated pathways, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::045624fd215b96e9d8bd06e2be876076
https://pubmed.ncbi.nlm.nih.gov/15488029

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Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo

Autor: G G, Vecil, P H, Larsen, S M, Corley, L M, Herx, A, Besson, C G, Goodyer, V W, Yong

Publikováno v: Journal of neuroscience research. 61(2)

An acute trauma to the CNS rapidly results in the upregulation of inflammatory cytokines that include interleukin-1 (IL-1). We report here that the levels of several matrix metalloproteinases (MMPs) are also elevated following a corticectomy trauma i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94effb314ae27561cbe2ac9a2fbb7f9e
https://pubmed.ncbi.nlm.nih.gov/10878594

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Pex/PEX tissue distribution and evidence for a deletion in the 3' region of the Pex gene in X-linked hypophosphatemic mice

Autor: Harriet S. Tenenhouse, Josée Martel, Claude Gauthier, G Krishnamurthy, C G Goodyer, Y Soumounou, Laurent Beck

PEX, a phosphate-regulating gene with homology to endopeptidases on the X chromosome, was recently identified as the candidate gene for X-linked hypophosphatemia. In the present study, we cloned mouse and human Pex/PEX cDNAs encoding part of the 5' u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6beaf0c88e59916bd6ad0566139616b
https://europepmc.org/articles/PMC507933/

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