Zobrazeno 1 - 10
of 10
pro vyhledávání: '"C F, Spraggs"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 272:G1243-G1248
Gastrin is the principal hormonal mediator of gastric acid secretion. Using an in vivo, intact, anesthetized rat model, we studied the role of gastrin/cholecystokinin (CCK)-B receptors in regulating the release of histamine and somatostatin during in
Publikováno v:
British journal of anaesthesia. 82(2)
In this double-blind, randomized, parallel group study, we have investigated the antiemetic activity of the potent and selective NK1 receptor antagonist GR205171 25 mg i.v. compared with placebo in the treatment of established postoperative nausea an
Autor:
A. K. Bahl, I. G. Oakley, Michael A. Trevethick, AP Dhillon, Andrew J. Wakefield, C. F. Spraggs, Roy E. Pounder, A Anthony
Publikováno v:
Side Effects of Anti-Inflammatory Drugs IV ISBN: 9789401062695
It is now widely accepted that the small intestine is an important site of non-steroidal antiinflammatory drug (NSAID)-induced inflammation and ulceration (Aabakken, 1992; Bjarnason et al, 1993). We described a sequence of 4 histologically distinct a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6803bd08ff9804ecfac9016e58284e8f
https://doi.org/10.1007/978-94-011-5394-2_51
https://doi.org/10.1007/978-94-011-5394-2_51
Autor:
A, Anthony, A K, Bahl, I G, Oakley, C F, Spraggs, A P, Dhillon, M A, Trevethick, C, Piasecki, R E, Pounder, A J, Wakefield
Publikováno v:
The Journal of pathology. 179(3)
Jejunal villi undergo early histological shortening and vascular injury in indomethacin-induced ulcerative enteropathy in the rat. The protective effects of the beta 3-adrenoceptor agonist CL316243 on this rat model and the mechanism of action were e
Publikováno v:
Alimentary pharmacologytherapeutics. 9(2)
SUMMARY Aims: To examine the effects of a pepsin inhibitor, pepstatin-A, a long acting H2-receptor blocker, loxtidine, exogenous pepsin and exogenous acid against indomethacin-induced antral ulceration in the rat. Results: Indomethacin (60 mg/kg s.c.
Publikováno v:
The Journal of physiology. 449
1. Transmucosal electrical resistance (Rt) and short-circuit current (Isc) were determined in rabbit isolated fundic mucosa. Under basal conditions, with a HCO(3-)-free HEPES-buffered solution (pH 7.4) bathing both sides of the mucosae, Rt was 161.5
Publikováno v:
Anesthesia & Analgesia. 86:436S
Autor:
K T Bunce, C F Spraggs
Publikováno v:
The Journal of pharmacy and pharmacology. 35(5)
Publikováno v:
The Journal of pharmacy and pharmacology. 35(4)
Autor:
C F Spraggs, K T Bunce
Publikováno v:
The Journal of physiology. 400
1. The effects of prostaglandin E2 (PGE2) on ion transport were investigated in guinea-pig isolated gastric mucosa. 2. Under resting conditions the mucosa produced a short-circuit current (SCC), the majority of which could be attributed to electrogen