Human fatty acid synthase mRNA: tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation

Autor: C F Semenkovich, T Coleman, F T Fiedorek, Jr

Publikováno v: Journal of Lipid Research, Vol 36, Iss 7, Pp 1507-1521 (1995)

To better understand the accelerated decay of fatty acid synthase (FAS) message that occurs after glucose deprivation (J. Biol. Chem. 1993. 268: 6961-6970), we characterized the 3‘ terminus of the human message and the kinetics of FAS mRNA decay in

Externí odkaz: https://doaj.org/article/5981d09f196e4e3e93fc1cc14d79fa85

Lipoprotein lipase and hepatic lipase mRNA tissue specific expression, developmental regulation, and evolution.

Autor: C F Semenkovich, S H Chen, M Wims, C C Luo, W H Li, L Chan

Publikováno v: Journal of Lipid Research, Vol 30, Iss 3, Pp 423-431 (1989)

Lipoprotein lipase (LPL) and hepatic lipase (HL) enzyme activities were previously reported to be regulated during development, but the underlying molecular events are unknown. In addition, little is known about LPL evolution. We cloned and sequenced

Externí odkaz: https://doaj.org/article/7b94da9ff39e4425989637aeaefc1fd3

Gut Dysbiosis Drives Inflammatory Bowel Disease Through the CCL4L2‐VSIR Axis in Glycogen Storage Disease.

Autor: Lan, Jiaoli^1,2 (AUTHOR), Zhang, Yuxin^1,3 (AUTHOR), Jin, Cuiyuan⁴ (AUTHOR), Chen, Huan⁵ (AUTHOR), Su, Zexiong¹ (AUTHOR), Wu, Jiaxing¹ (AUTHOR), Ma, Ni¹ (AUTHOR), Zhang, Xiaoyan¹ (AUTHOR), Lu, Yiyun¹ (AUTHOR), Chen, Yongxin¹ (AUTHOR), Zeng, Xiaolu¹ (AUTHOR), Zhang, Huiqiong¹ (AUTHOR), Zheng, Guilang¹ (AUTHOR), Sun, Yueyu¹ (AUTHOR), Wang, Chun¹ (AUTHOR), Hu, Yan¹ (AUTHOR), Wang, Yifei¹ (AUTHOR), Liu, Yumei¹ (AUTHOR), Zeng, Zhaoyang⁴ (AUTHOR), Shi, Liyun⁴ (AUTHOR)

Publikováno v: Advanced Science. 8/14/2024, Vol. 11 Issue 30, p1-19. 19p.

Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction

Autor: W S, Cruz, G, Kwon, C A, Marshall, M L, McDaniel, C F, Semenkovich

Publikováno v: The Journal of biological chemistry. 276(15)

Lipoprotein lipase (LpL) provides tissues with triglyceride-derived fatty acids. Fatty acids affect beta-cell function, and LpL overexpression decreases insulin secretion in cell lines, but whether LpL is regulated in beta-cells is unknown. To test t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ba667d7efaefe211b9778865427719d
https://pubmed.ncbi.nlm.nih.gov/11154699

Skeletal muscle lipoprotein lipase: molecular regulation and physiological effects in relation to exercise

Autor: R L, Seip, C F, Semenkovich

Publikováno v: Exercise and sport sciences reviews. 26

LPL directs the body wide distribution of fatty acids derived from circulating triglycerides. This is accomplished by tissue-specific regulation. In adipose tissue, LPLA per gram is higher than in muscle tissue. Eating increases adipose tissue LPLA a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6759d9dda03b6cf8086792d34b2501f8
https://pubmed.ncbi.nlm.nih.gov/9696990