Zobrazeno 1 - 10
of 33
pro vyhledávání: '"C F, Schaefer"'
Publikováno v:
SEG Discovery. :1-19
Publikováno v:
Free Radical Biology and Medicine. 21:427-436
For greatest efficacy, it is desirable to use spin trapping agents in the highest concentrations possible. Fifty-four male Sprague-Dawley rats were used to explore the relative toxicity of four representative nitronyl spin traps at doses chosen on th
Publikováno v:
Journal of Biochemical and Biophysical Methods. 30:239-247
To obtain the strongest possible free radical spin adduct signal using the electron paramagnetic resonance spectroscopy-spin trapping technique, it is desirable to load an animal with the highest dose of spin trap possible. One hundred and twenty six
Autor:
Daniel J. Brackett, Megan R. Lerner, C. F. Schaefer, Lennart Fagraeus, John W. Holaday, Michael F. Wilson
Publikováno v:
Regulatory Peptides. 29:153-162
Thyrotropin releasing hormone (TRH) has been reported to reduce endotoxin-induced hypotension and mortality rate in conscious rats. Limited data are available to explain these effects. We evaluated hemodynamic parameters, metabolic function, tissue i
Publikováno v:
Acta anaesthesiologica Scandinavica. 39(1)
A colloid (Hespan®) fluid regimen in a 4 h rat model of endotoxaemia was used to prevent the development of the early hypodynamic phase of shock. Groups (N=10 each) of isoflurane-anaesthetized, male Sprague-Dawley rats received either 1) E. coli end
Autor:
C F, Schaefer, B, Biber
Publikováno v:
Circulatory shock. 40(1)
We conducted the present study to determine the effect of endotoxin challenge on brain oxidative metabolism, after finding evidence in previous studies suggesting early uncoupling of mitochondrial oxidative phosphorylation in the rat small intestine
Publikováno v:
The Journal of surgical research. 51(5)
In vivo near-infrared spectrophotometry was used to determine whether lethal endotoxemia impairs small intestinal oxidative phosphorylation as reflected by the redox state of mitochondrial cytochrome a,a3 (AA3). Adult male Sprague-Dawley rats were an
Publikováno v:
Circulatory shock. 33(1)
Dose-related, endotoxin-induced changes in oxidative metabolism were investigated in vivo using near-infrared spectrophotometry. Sixty fasted male Sprague-Dawley rats were randomly allocated to groups (N = 10 each) receiving saline, 0.08, 0.3, 1.25,