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Metabolism and disposition of a thiazolobenzimidazole active against human immunodeficiency virus-1

Autor: S M, el Dareer, K F, Tillery, L M, Rose, C F, Posey, R F, Struck, S W, Stiller, D L, Hill

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 21(2)

This study was undertaken to evaluate the disposition of the thiazolobenzimidazole, 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole (TZB), which has promising antiviral activity. For mice, the maximum tolerated intravenous dose of TZB was 5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60a6bb3c3ae9fc1fd9f8d45580e12684
https://pubmed.ncbi.nlm.nih.gov/8097690

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