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Autor:
C F, Pocock, F E, Cotter
Publikováno v:
Methods in molecular medicine. 6
Chromosome rearrangements of chromosome 11 at band 1 1q23 are detected in a high proportion of infant leukemias (l yr) as well as childhood and adult acute leukemlas of both myelold and lymphold types. Molecular and cytogenetic analysis of these tumo
Publikováno v:
British journal of haematology. 90(4)
Acute leukaemia of infancy is associated with abnormalities at chromosome band 11q23, and has a poor prognosis. The gene involved. Mixed Lineage Leukaemia (MLL), has been identified and has the characteristics of a transcription factor. The BCL-2 gen