Zobrazeno 1 - 10
of 69
pro vyhledávání: '"C F, Meares"'
Publikováno v:
Biochemistry. 40:3184-3188
By exploiting substrate protection of Cys148 in lactose permease, a methanethiosulfonate nitroxide spin-label was directed specifically to one of two Cys residues in a double-Cys mutant, followed by labeling of Cys148 with a thiol-reactive chelator t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d43482bba04ec1cf8183bba4fa3dc8
https://doi.org/10.1021/bi002333e
https://doi.org/10.1021/bi002333e
Autor:
Donald T. Corson, C F Meares
Publikováno v:
Bioconjugate Chemistry. 11:292-299
We have developed and optimized the synthesis of the title compound, eliminating all HPLC purifications prior to the final product. The yield (and scale) of the synthesis was increased from 19% (200 mg) to 75% (26 g).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a4ee615e98ab8698a096a93585e4427
https://doi.org/10.1021/bc990125x
https://doi.org/10.1021/bc990125x
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 51:621-623
The structure was solved by the Patterson method and suc- cessive Fourier electron density difference maps, and refined by full-matrix least-squares procedures with anisotropic tem- perature factors for all non-H atoms. The positions of all H atoms w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d66017f9d0b7058945437e3980cafe3d
https://doi.org/10.1107/s0108270194011753
https://doi.org/10.1107/s0108270194011753
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(9)
Radiometal-labeled monoclonal antibodies are retained longer in tumors than iodinated antibodies, leading to their increased use for radioimmunotherapy. Dissociation of radioiodine from the antibody during metabolism has been documented. We now repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed51aae3c56bcfe22dc31eb8b0d66d56
https://pubmed.ncbi.nlm.nih.gov/11535720
https://pubmed.ncbi.nlm.nih.gov/11535720
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(4)
Biodistribution and dosimetry of 88Y (and equimolar 90Y) Janus-dodecanetetraacetic acid (DOTA) were performed using a three-step pretargeting protocol in BALB/c mice bearing mouse mammary adenocarcinoma (KHJJ) implants. Pretargeting was performed wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3266fb15eac810208ae18a5a0c7fb49a
https://pubmed.ncbi.nlm.nih.gov/11337558
https://pubmed.ncbi.nlm.nih.gov/11337558
Autor:
S A, Datwyler, C F, Meares
Publikováno v:
Metal ions in biological systems. 38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37a71accfb271b0681a265f6812a9e29
https://pubmed.ncbi.nlm.nih.gov/11219010
https://pubmed.ncbi.nlm.nih.gov/11219010
Autor:
S. A. Datwyler, C. F. Meares
Publikováno v:
Trends in biochemical sciences. 25(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582778f5b4330a25712b207a623fe71d
https://pubmed.ncbi.nlm.nih.gov/11050426
https://pubmed.ncbi.nlm.nih.gov/11050426
Autor:
G L, DeNardo, R T, O'Donnell, S, Shen, L A, Kroger, A, Yuan, C F, Meares, D L, Kukis, S J, DeNardo
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(5)
Several monoclonal antibodies, including Lym-1, have proven effective for treatment of hematologic malignancies. Lym-1, which preferentially targets malignant lymphocytes, has induced therapeutic responses and prolonged survival in patients with non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cef01ac4bc4a2091141af2b93c3b0e23
https://pubmed.ncbi.nlm.nih.gov/10809213
https://pubmed.ncbi.nlm.nih.gov/10809213
Autor:
C F, Meares
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da69acc3211d8be6946d58bc045d4934
https://pubmed.ncbi.nlm.nih.gov/10541332
https://pubmed.ncbi.nlm.nih.gov/10541332
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(3)
Antilymphoma mouse monoclonal antibody (MoAb) Lym-1, labeled with 67Cu or 131I, has demonstrated promising results in radioimmunotherapy (RIT) for lymphoma. Although 131I has played a central role in RIT thus far, some properties of 67Cu are preferab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::496fcb452f073cd5931ea72cb5453f46
https://pubmed.ncbi.nlm.nih.gov/10100704
https://pubmed.ncbi.nlm.nih.gov/10100704