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Autor:
G M, Vandeplassche, C F, Hermans, D R, de Chaffoy de Courcelles, J A, D'Aubioul, L J, Wouters, F F, De Clerck
Publikováno v:
Journal of cardiovascular pharmacology. 19(5)
Using different subtypes of cyclic nucleotide phosphodiesterase (PDE) isoenzymes isolated from canine left ventricle, we identified R 80122, a 1,2,3,5-tetrahydro2-oxoimidazo[2,1-b]quinazoline derivative that was a more selective and potent inhibitor