Zobrazeno 1 - 10
of 43
pro vyhledávání: '"C F, Abildgaard"'
Autor:
Jeanne M. Lusher, P. M. Mannucci, Steven Arkin, D. Hurst, C F Abildgaard, L. Schwartz, R. Zimmermann
Publikováno v:
Journal of Thrombosis and Haemostasis. 2:574-583
Summary. Background: Development of recombinant factor VIII (rFVIII) replacement therapy represents a milestone in the treatment of hemophilia A. Objective: The objective of this long-term, multicenter study was to assess the safety, efficacy and rat
Publikováno v:
Haemophilia. 5:9-16
Fifty-eight previously treated haemophilic subjects were treated exclusively with the recombinant FVIII (rFVIII-KOGENATE) produced by Bayer Corporation (Berkeley, CA) in an international multicentre prospective study of more than 5 years duration. Fi
Autor:
D Hurst, Louis M. Aledort, P. M. Mannucci, C F Abildgaard, R S Schwartz, Doreen B. Brettler, Jeanne M. Lusher
Publikováno v:
Blood. 83:1958-1962
Recent studies suggest that treatment of hemophiliacs with highly purified factor VIII concentrates may preserve immune function. To test this hypothesis, we prospectively studied 51 hemophilic patients (21 human immunodeficiency virus [HIV] seroposi
Autor:
Carol K. Kasper, JeanneM. Lusher, J Addiego, Bertil Glader, C F Abildgaard, L Aledort, Margaret W. Hilgartner
Publikováno v:
The Lancet. 342:462-464
Clinical studies evaluating highly purified monoclonal-antibody-derived and recombinant-DNA-derived clotting factor concentrates in previously untreated (PUPS) severe factor VIII (FVIII) deficient haemophilia patients, have documented an increased fr
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 5(1)
Fifty-eight previously treated haemophilic subjects were treated exclusively with the recombinant FVIII (rFVIII-KOGENATE) produced by Bayer Corporation (Berkeley, CA) in an international multicentre prospective study of more than 5 years duration. Fi
Publikováno v:
American Journal of Public Health. 80:967-969
Thirteen hemophilia centers provide comprehensive care to approximately 90 percent of persons with hemophilia in California. For 1987, these centers reported patient human immunodeficiency virus (HIV) antibody status, age group, level of clotting fac
Autor:
M A, Jarvis, L G, Levin, J A, Harrison, D J, DePianto, C M, Suzuki, C L, Ziaja, J E, Brown, K W, Jolly, H M, Reisner, C F, Abildgaard, J S, Powell
Publikováno v:
Thrombosis and haemostasis. 75(2)
Hemophilia A is a clotting disorder that is due to reduced or absent coagulation factor VIII (FVIII) activity. In approximately 25% of people with severe hemophilia A, standard treatment with intravenous plasma-derived or recombinant FVIII (rFVIII) i
Publikováno v:
The American journal of pediatric hematology/oncology. 15(3)
Alpha 2-Antiplasmin (AP) deficiency is a rare congenital bleeding disorder that presents with normal screening tests for platelet function and clotting. We believe that this disorder is frequently overlooked, especially in women with unexplained blee
Publikováno v:
The New England journal of medicine. 328(7)
Although methods of viral attenuation in plasma-derived clotting-factor concentrates have improved, there is still a possibility that such concentrates may transmit certain blood-borne viruses. For this reason, the use of recombinant DNA-derived fact
Autor:
C F, Abildgaard
Publikováno v:
Seminars in hematology. 28(2 Suppl 1)