Zobrazeno 1 - 10
of 115
pro vyhledávání: '"C Elrod"'
Antiviral screening of natural, anti-inflammatory compound library against African swine fever virus
Autor:
Joshua A. Jackman, Astghik Hakobyan, Rafayela Grigoryan, Roza Izmailyan, Charles C. Elrod, Hovakim Zakaryan
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background African swine fever virus (ASFV) is a major threat to pig production and the lack of effective vaccines underscores the need to develop robust antiviral countermeasures. Pathologically, a significant elevation in pro-inflammatory
Externí odkaz:
https://doaj.org/article/c9b71f7c0b5f40f7b09efdaa75a42bab
Publikováno v:
Pathogens, Vol 12, Iss 10, p 1193 (2023)
Naturally abundant antimicrobial lipids, such as fatty acids and monoglycerides, that disrupt membrane-enveloped viruses are promising mitigants to inhibit African swine fever virus (ASFV). Among mitigant candidates in this class, glycerol monolaurat
Externí odkaz:
https://doaj.org/article/2f51866540f444ae93d036bf52c055e2
Publikováno v:
Frontiers in Animal Science, Vol 3 (2022)
The development of natural, broadly acting antimicrobial solutions to combat viral and bacterial pathogens is a high priority for the livestock industry. Herein, we cover the latest progress in utilizing lipid-based monoglycerides as feed additives t
Externí odkaz:
https://doaj.org/article/83ace8f81d994e8bb83bd5ffcfe39061
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 11, Iss 1, Pp 1-10 (2020)
Abstract Background The ongoing African swine fever virus (ASFv) epidemic has had a major impact on pig production globally and biosecurity efforts to curb ASFv infectivity and transmission are a high priority. It has been recently identified that fe
Externí odkaz:
https://doaj.org/article/21f8157f91044199b094c868c9399926
Autor:
S. E. Sivinski, L. K. Mamedova, R. A. Rusk, C. C. Elrod, T. H. Swartz, J. M. McGill, B. J. Bradford
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 11, Iss 1, Pp 1-10 (2020)
Abstract Background While feed components capable of modulating the immune system are highly sought after and marketed, often little evidence is available to support functional immune response claims. Thus, a high-throughput in vitro cell screening s
Externí odkaz:
https://doaj.org/article/b3d07cc358cc45e8994a6cf162b9c1e1
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Ongoing challenges in the swine industry, such as reduced access to antibiotics and virus outbreaks (e.g., porcine epidemic diarrhea virus, African swine fever virus), have prompted calls for innovative feed additives to support pig producti
Externí odkaz:
https://doaj.org/article/aff1a150f94d4c4a9fec4890b14e8a45
Autor:
Erik Arabyan, Astghik Hakobyan, Tamara Hakobyan, Rafaella Grigoryan, Roza Izmailyan, Aida Avetisyan, Zaven Karalyan, Joshua A. Jackman, Fernando Ferreira, Charles C. Elrod, Hovakim Zakaryan
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Naturally occurring plant flavonoids are a promising class of antiviral agents to inhibit African swine fever virus (ASFV), which causes highly fatal disease in pigs and is a major threat to the swine industry. Currently known flavonoids with anti-AS
Externí odkaz:
https://doaj.org/article/ba1d5b4bdc5849e4acd46eb981b52b0f
Self-Assembled Nickel-4 Supramolecular Squares and Assays for HER Electrocatalysts Derived Therefrom
Autor:
Wenting Mo, Christopher R DeLaney, Nattamai Bhuvanesh, Xuemei Yang, Michael B. Hall, Kyle T. Burns, Marcetta Y. Darensbourg, Lindy C Elrod, Haley Naumann
Publikováno v:
Inorganic Chemistry. 60:7051-7061
Solid-state structures find a self-assembled tetrameric nickel cage with carboxylate linkages, [Ni(N2S'O)I(CH3CN)]4 ([Ni-I]40), resulting from sulfur acetylation by sodium iodoacetate of an [NiN2S]22+ dimer in acetonitrile. Various synthetic routes t
Autor:
Manuel Quiroz, Molly M. Lockart, Mohamed R. Saber, Shaik Waseem Vali, Lindy C. Elrod, Brad S. Pierce, Michael B. Hall, Marcetta Y. Darensbourg
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The synthesis of sulfur-bridged Fe–Ni heterobimetallics was inspired by Nature’s strategies to “trick” abundant first row transition metals into enabling 2-electron processes: redox-active ligands (including pendant iron–sulfur clusters) an
Autor:
Donald J. Darensbourg, Chung-H Hsieh, Marcetta Y. Darensbourg, Nattamai Bhuvanesh, Lindy C Elrod, Pokhraj Ghosh, Kavindu Dilshan Kariyawasam Pathirana
Publikováno v:
Inorganic Chemistry. 59:3753-3763
The development of ligands with specific stereo- and electrochemical requirements that are necessary for catalyst design challenges synthetic chemists in academia and industry. The crucial aza-dithiolate linker in the active site of [FeFe]-H2ase has