Zobrazeno 1 - 10
of 29
pro vyhledávání: '"C Edwin Garner"'
Autor:
Tuvshintugs Baljinnyam, Yosuke Niimi, John R. Salsbury, Satoshi Fukuda, Casey M. Ouellette, Clark R. Andersen, Yasutaka Hirasawa, Donald A. Prough, C. Edwin Garner, Andrew L. Salzman, Perenlei Enkhbaatar
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Characterization of the pathophysiology of ARDS following chlorine gas inhalation in clinically relevant translational large animal models is essential, as the opportunity for clinical trials in this type of trauma is extremely limited. To i
Externí odkaz:
https://doaj.org/article/92f5f5112ba446bf8f9d92c0a9c0e0f1
Autor:
Satoshi Fukuda, Yosuke Niimi, Yasutaka Hirasawa, Ennert R. Manyeza, C. Edwin Garner, Garry Southan, Andrew L. Salzman, Donald S. Prough, Perenlei Enkhbaatar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In sepsis, microvascular hyperpermeability caused by oxidative/nitrosative stress (O&NS) plays an important role in tissue edema leading to multi-organ dysfunctions and increased mortality. We hypothesized that a novel compound R-107, a modu
Externí odkaz:
https://doaj.org/article/0a205f198d544ea58822c974d20c9099
Autor:
C. Edwin Garner, Christopher J. Wegerski, Melanie Doyle-Eisele, Jacob D. McDonald, J. Michael Sanders, Benjamin C. Moeller, Suramya Waidyanatha
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 883-892 (2020)
2′,2′′′-Dithiobisbenzanilide (DTBBA) is a high-production-volume chemical used as a peptizing agent for rubber. The disposition and metabolism of [14C]DTBBA were determined in male and female rats and mice following oral (4, 40, or 400 mg/kg)
Externí odkaz:
https://doaj.org/article/ccfc7d63e08048ffa968a1f99f964164
Autor:
J. Michael Sanders, Jacob D. McDonald, Benjamin C. Moeller, Suramya Waidyanatha, Melanie Doyle-Eisele, C. Edwin Garner, Christopher J. Wegerski
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 883-892 (2020)
Toxicology Reports, Vol 7, Iss, Pp 883-892 (2020)
Highlights • 2′,2′′′-Dithiobisbenzanilide (DTBBA) is a chemical used as a peptizing agent for rubber. • Humane exposure to DTBBA is possible via oral and dermal routes. • DTBBA is well-absorbed in rodents following oral and dermal admin
Autor:
Mitsuo Hinoue, Toru Ishidao, C Edwin Garner, Hajime Hori, Mizuki Matsuno, Yukiko Fueta, Hazuki Noguchi
Publikováno v:
Industrial Health
Previously, we reported that prenatal exposure to 1-bromopropane (1-BP) causes the accumulation of bromide (Br-) in the brain of rat pups. Here, we aimed to investigate the effects of Br- accumulation in rat pups prenatally exposed to 1-BP vapor. Dam
Autor:
Christopher J. Wegerski, Jacob D. McDonald, Suramya Waidyanatha, Barry S. McIntyre, C. Edwin Garner, Melanie Doyle-Eisele, Esra Mutlu
Publikováno v:
Xenobiotica
1. 2-Hydroxy-4-methoxybenzophenone (HMB) is a common ingredient in personal care products and used as an UV stabilizer. In these studies, disposition and metabolism of [(14)C]HMB in rats and mice was assessed following single gavage administration (1
Autor:
J. Michael Sanders, Benjamin C. Moeller, Suramya Waidyanatha, C. Edwin Garner, Melanie Doyle-Eisele, Jacob D. McDonald
The specialty amine catalyst 2,2′-dimorpholinodiethyl ether (DMDEE) is a high-production volume chemical used in the production of flexible foam, high-resilient molded foam, and in coatings and adhesives. The disposition and metabolism of [14C]DMDE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4968a8e1e33a7b368a80cee85b231dec
Autor:
C. Edwin Garner, Kristen Ryan, Christopher J. Wegerski, Suramya Waidyanatha, Jacob D. McDonald, Melanie Doyle-Eisle, J. Michael Sanders
Publikováno v:
Toxicology and Applied Pharmacology. 339:151-160
β-N-methylamino-l-alanine (L-BMAA) is produced by cyanobacteria (blue-green algae). Human exposure to L-BMAA occurs via consumption of L-BMAA-contaminated water and food. It is speculated that exposure to L-BMAA, and subsequent brain accumulation, m
Autor:
Benjamin C. Moeller, Jacob D. McDonald, Philip J. Kuehl, Brenna Espelien, Waylon Weber, Robert Raulli, Efrain Garcia, Judith Laney, C. Edwin Garner, Melanie Doyle-Eisele
Publikováno v:
Drug testing and analysis, vol 11, iss 1
Moeller, Benjamin; Espelien, Brenna; Weber, Waylon; Kuehl, Philip; Doyle-Eisele, Melanie; Garner, C Edwin; et al.(2019). The pharmacokinetics of ketamine following intramuscular injection to F344 rats.. Drug testing and analysis, 11(1), 68-76. doi: 10.1002/dta.2468. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2qb0b1jz
Moeller, Benjamin; Espelien, Brenna; Weber, Waylon; Kuehl, Philip; Doyle-Eisele, Melanie; Garner, C Edwin; et al.(2019). The pharmacokinetics of ketamine following intramuscular injection to F344 rats.. Drug testing and analysis, 11(1), 68-76. doi: 10.1002/dta.2468. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2qb0b1jz
Ketamine is a glutamate N-methyl-D-aspartate receptor antagonist that is a rapid acting dissociative anesthetic. It has been proposed to be an adjuvant treatment along with other drugs (atropine, midazolam, pralidoxime) used in the current standard o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513408ff8a84c9efd606253e71027a83
https://escholarship.org/uc/item/2qb0b1jz
https://escholarship.org/uc/item/2qb0b1jz
Autor:
Chinyen Huang, Xiao Zhang, C. Edwin Garner, Sahoko Ichihara, Jie Chang, Gaku Ichihara, Toshihiro Sakurai, Masashi Kato, Cai Zong
Publikováno v:
Toxicology Research. 5:1522-1529
1-Bromopropane (1BP) is widely used as an alternative to ozone-depleting solvents. The present study investigated the role of P450s in 1BP-induced male reproductive toxicity. Mice co-treated with 1-aminobenzotriazole (ABT), a non-selective P450 inhib