Zobrazeno 1 - 10
of 40
pro vyhledávání: '"C E Halstenson"'
Publikováno v:
Investigational New Drugs
SummaryBackground BTH1677 is a beta glucan pathogen associated molecular pattern (PAMP) currently being investigated as a novel cancer therapy. Here, the initial safety and pharmacokinetic (PK) results of BTH1677 in healthy subjects are reported. Sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f694b48764f3450bd533caad0adc5d09
https://doi.org/10.1007/s10637-016-0325-z
https://doi.org/10.1007/s10637-016-0325-z
Autor:
S Anjum, D. L. Cutler, M.B. Affrime, Lawrence J. Lambrecht, Elaine Radwanski, Suzanne K. Swan, C E Halstenson
Publikováno v:
British Journal of Clinical Pharmacology. 47:43-47
Aims The aim of this study was to determine the pharmacokinetic parameters of flutamide, a nonsteroidal antiandrogenic compound, and its pharmacologically active metabolite, hydroxyflutamide, in renal insufficiency. Haemodialysis (HD) clearance of fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc7e1f4d6ad339acc92a54a5cdd76ae
https://doi.org/10.1046/j.1365-2125.1999.00831.x
https://doi.org/10.1046/j.1365-2125.1999.00831.x
Autor:
Joan M. Korth-Bradley, C E Halstenson, Kavita Gumbhir-Shah, Sheryl A Decleene, William H. Cevallos
Publikováno v:
Annals of Pharmacotherapy. 31:395-399
Objective To estimate absolute bioavailability of bromfenac and to compare its pharmacokinetics after intravenous and oral administration. Design This was a randomized, open-label, single-dose, crossover study conducted under fasting conditions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034d1bce021c86c525f57982f75f5aea
https://doi.org/10.1177/106002809703100401
https://doi.org/10.1177/106002809703100401
Publikováno v:
The Journal of Clinical Pharmacology. 35:384-389
The disposition of misoprostol acid, the active metabolite of misoprostol, was studied in 48 subjects with various degrees of renal function after administration of a single 400 microgram oral dose of misoprostol. Subjects were assigned to one of fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054af21cd8ea3418885a3c5461355884
https://doi.org/10.1002/j.1552-4604.1995.tb04078.x
https://doi.org/10.1002/j.1552-4604.1995.tb04078.x
Autor:
Thomas A. Golper, E.D. Everett, Henri A. Verbrugh, William F. Keane, C E Halstenson, R. Gokal, Stephen I. Vas, Yoshindo Kawaguchi, Miguel C. Riella
Publikováno v:
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis. 13:14-18
In conclusion, the recommendations provided in this document represent a distillation of various experiences, as well as data obtained from published studies. It is hoped that this compilation will provide a basis upon which future developments and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a5b3e14f9e7f6bd845a18111877465d
https://doi.org/10.1177/089686089301300106
https://doi.org/10.1177/089686089301300106
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:126-131
The disposition of cefpodoxime in 24 subjects with various degrees of renal function after administration of a single oral dose of 200 mg of cefpodoxime proxetil (equivalent to 200 mg of cefpodoxime activity) was studied. Subjects were assigned to on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88531f5a855fc8ae9bdd48c4382ceac9
https://doi.org/10.1128/aac.36.1.126
https://doi.org/10.1128/aac.36.1.126
Autor:
Melton B. Affrime, Judy Shepard Kelloway, Josephine Lim, C E Halstenson, Gary R. Matzke, Chin C. Lin, William F. Keane, Walid M. Awni
Publikováno v:
Antimicrobial Agents and Chemotherapy. 35:2267-2274
The impact of renal insufficiency on the dispositions of 300 mg of orally administered ceftibuten-cis, a new broad-spectrum oral cephalosporin, and its primary metabolite ceftibuten-trans was characterized in 30 adult subjects. Subjects were divided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8867e0a66c8e4b947339aeec1648be
https://doi.org/10.1128/aac.35.11.2267
https://doi.org/10.1128/aac.35.11.2267
Publikováno v:
Annals of Emergency Medicine. 20:536-539
To determine if gastrointestinal decontamination using whole-bowel irrigation (WBI) was an effective treatment for acute ingestion of sustained-release lithium.In a two-phase, crossover protocol, ten normal volunteers ingested in each phase 0.80 mEq/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a162873998c28551591006af5048363
https://doi.org/10.1016/s0196-0644(05)81610-5
https://doi.org/10.1016/s0196-0644(05)81610-5
Autor:
H. Ko, K. S. Cathcart, John A. Opsahl, L. S. Olanoff, Gary R. Matzke, C E Halstenson, C. A. I. Hirata, D. R. P. Guay, E. Novak
Publikováno v:
Antimicrobial Agents and Chemotherapy. 34:519-523
The disposition of cefmetazole was studied in 25 subjects with various degrees of renal function after a 1,000-mg, constant-rate, 30-min intravenous infusion of cefmetazole sodium. In six subjects with creatinine clearance (CLCR) of greater than 90 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1077567b2550005cef266032b08bd1
https://doi.org/10.1128/aac.34.4.519
https://doi.org/10.1128/aac.34.4.519
Autor:
Richard A. Couch, Elizabeth Slaughter, C E Halstenson, Susan P. Browne, Yuxin Zhang, Angus M. McLean
Publikováno v:
Journal of clinical pharmacology. 41(2)
Carbatrol, a new dosage form of carbamazepine (CBZ), was developed consisting of three different types of pellets (immediate release, controlled release, and enteric release). The objective of this study was to explore the influence of food on absorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed91b0f9ee50839607dec66f7610e389
https://pubmed.ncbi.nlm.nih.gov/11210399
https://pubmed.ncbi.nlm.nih.gov/11210399