Výsledky vyhledávání - "C E Grimshaw"

Characterization and nucleotide binding properties of a mutant dihydropteridine reductase containing an aspartate 37-isoleucine replacement

Autor: Tom Bray, M. Skinner, Kottayil I. Varughese, Nguyen-Huu Xuong, D.A. Matthews, James A. Hoch, J. M. Whiteley, C E Grimshaw

Publikováno v: Journal of Biological Chemistry. 267:15334-15339

Kinetic constants for the interaction of NADH and NADPH with native rat dihydropteridine reductase (DHPR) and an Escherichia coli expressed mutant (D-37-I) have been determined. Comparison of kcat and Km values measured employing quinonoid 6,7-dimeth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a16f0f303bcfbcea3b6cb7b0e2cf44a
https://doi.org/10.1016/s0021-9258(19)49538-0

Zobrazit plný text záznamu

Sequence analysis of bovine lens aldose reductase

Autor: S L Early, C C Doughty, R L Heinrikson, F J Kézdy, T R Williams, C E Grimshaw, S Z Schade

Publikováno v: Journal of Biological Chemistry. 265:3628-3635

The covalent structure of bovine lens aldose reductase (alditol-NADP+ oxidoreductase, EC 1.1.1.21) was determined by sequence analysis of peptides generated by specific and chemical cleavage of the homogeneous apoenzyme. Peptides, purified by reverse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45dfa364eb1e732bed5c9ea3d13024cb
https://doi.org/10.1016/s0021-9258(19)39639-5

Zobrazit plný text záznamu

A source of response regulator autophosphatase activity: the critical role of a residue adjacent to the Spo0F autophosphorylation active site

Autor: Kottayil I. Varughese, Madhusudan M, James Zapf, James A. Hoch, J. M. Whiteley, C E Grimshaw

Publikováno v: Biochemistry. 37(21)

Two-component signaling systems are used by bacteria, plants, and lower eukaryotes to adapt to environmental changes. The first component, a protein kinase, responds to a signal by phosphorylating the second component; a response regulator protein th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5893731c6d02a0d8f3fc1458d83cc11d
https://pubmed.ncbi.nlm.nih.gov/9601032

Zobrazit plný text záznamu