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Pattern recognition receptors in equine endotoxaemia and sepsis

Autor: C. E. Bryant, A. H. Werners

Publikováno v: Equine Veterinary Journal. 44:490-498

Pattern recognition receptors (PRRs) on host cells detect pathogens to activate innate immunity which, in turn, initiates inflammatory and adaptive immune responses. Successful activation of PRRs is, therefore, critical to controlling infections and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db9541521df6db6b742adb2171328c26
https://doi.org/10.1111/j.2042-3306.2012.00574.x

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Effect of the inducible nitric oxide synthase inhibitors aminoguanidine and L-N6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin

Autor: V C Ridger, E R Pettipher, C E Bryant, S D Brain

Publikováno v: The Journal of Immunology. 159:383-390

The effect of nitric oxide synthase (NOS) inhibitors on plasma extravasation in a rat model of zymosan-induced inflammation has been investigated. Plasma extravasation was determined in response to intradermal test agents over 0 to 45 min or 0 to 4 h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d98a5d2f2b51d4f422c9803b33d97e9a
https://doi.org/10.4049/jimmunol.159.1.383

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The actions of medetomidine may not be mediated exclusively by α2-adrenoceptors in the equine saphenous vein

Autor: K.W. Clarke, C. E. Bryant

Publikováno v: Journal of Veterinary Pharmacology and Therapeutics. 19:124-129

Spirals of endothelially denuded equine saphenous vein were used to study the pre- and post-junctional effects of medetomidine in vitro. The pD2 values were calculated for noradrenaline (6.7 +/- 0.1), phenylephrine (5.6 +/- 0.1), BHT 920 (6.2 +/- 0.2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2d89bab5cbc23b4f8295f87dd36ba4
https://doi.org/10.1111/j.1365-2885.1996.tb00024.x

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Pattern recognition receptors in equine endotoxaemia and sepsis

Autor: A H, Werners, C E, Bryant

Publikováno v: Equine Veterinary Journal

Summary Pattern recognition receptors (PRRs) on host cells detect pathogens to activate innate immunity which, in turn, initiates inflammatory and adaptive immune responses. Successful activation of PRRs is, therefore, critical to controlling infecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1fd71c3f2279b32927c52df5fe2f0d2
https://pubmed.ncbi.nlm.nih.gov/22607193

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Suppression by dexamethasone of inducible nitric oxide synthase protein expression in vivo: a possible role for lipocortin 1

Autor: C E, Bryant, M, Perretti, R J, Flower

Publikováno v: Biochemical pharmacology. 55(3)

Western blot and densitometric analysis of organ homogenates from lipopolysaccharide (LPS)-treated rats (1-10 mg kg(-1), i.p.) exhibited a strong induction of inducible nitric oxide synthase (iNOS) expression seen at all the doses tested (1, 3, and 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::860180f588088b771d45f43e0f76c4b4
https://pubmed.ncbi.nlm.nih.gov/9484793

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Effect of the inducible nitric oxide synthase inhibitors aminoguanidine and L-N6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin

Autor: V C, Ridger, E R, Pettipher, C E, Bryant, S D, Brain

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 159(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f087630725c73c622dad9450161f9c1d
https://pubmed.ncbi.nlm.nih.gov/9200477

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