Zobrazeno 1 - 10
of 30
pro vyhledávání: '"C E, Uboh"'
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 35:1-12
This review presents a brief historical prospective of the genesis of regulated medication in the US racing industry of which the nonsteroidal anti-inflammatory drug (NSAID) phenylbutazone (PBZ) is the focus. It presents some historical guideposts in
Autor:
C. E. Uboh, Peter J. Moate, A. W. van Eps, Bernd Driessen, Lawrence R. Soma, Y. Liu, R. L. Terry, Sue M. McDonnell
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 33:485-494
Gabapentin is being used in horses although its pharmacokinetic (PK) profile, pharmacodynamic (PD) effects and safety in the equine are not fully investigated. Therefore, we characterized PKs and cardiovascular and behavioral effects of gabapentin in
Publikováno v:
International Journal of Sports Medicine. 30:80-86
Darbepoetin alfa (DPO) or Novel Erythropoiesis Erythropoiesis Stimulating Protein (NESP), an analog of recombinant human erythropoietin (rhEPO), is abused as a blood doping agent along with the latter in human sports. This paper describes a new metho
Publikováno v:
Analytical Chemistry. 76:5127-5135
Oxyglobin (OXY) and Hemopure (HMP) are produced from bovine hemoglobin (Hb) and were developed for the treatment of anemia in animal and human patients, respectively. Hemolink (HML) is a blood substitute of human Hb origin under development. The abil
Autor:
D. Teleis, Laura May, Jeffrey A. Rudy, C. E. Uboh, Yi Luo, Mary A. Fennell, Anthony O. Watson, Lawrence R. Soma, Elizabeth McNamara
Publikováno v:
American Journal of Veterinary Research. 61:811-815
Objective—To compare the pharmacokinetics of penicillin G and procaine in racehorses following IM administration of penicillin G procaine (PGP) with pharmacokinetics following IM administration of penicillin G potassium and procaine hydrochloride (
Autor:
C. E. Uboh, Lawrence R. Soma
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 21:228-240
Furosemide has been used empirically and has been legally approved for many years by the US racing industry for the control of exercise-induced pulmonary haemorrhage (EIPH) or bleeding. Its use in horses for this purpose is highly controversial and h
Publikováno v:
Equine Veterinary Journal. 28:390-396
The administration of sodium bicarbonate (NaHCO3) or 'milk shakes' to Standardbred horses before racing is widespread. This study analysed nonrace day (CTL) and prerace venous acid-base values from Standardbred horses racing in Pennsylvania (PA) and
Autor:
John M. Leonard, Frank A. Railing, Judith M. Shoemaker, Jeffrey A. Rudy, Lawrence R. Soma, John M. Shellenberger, Zoltan Kemecsei, James M. Enright, Dwarika N. Das, Mark C. Kahler, C. E. Uboh
Publikováno v:
Journal of Analytical Toxicology. 19:307-315
Although urine is the sample of choice for drug tests in racehorses, it is rarely obtained following the sudden death of a racehorse on the track while racing. The purpose of this study was to demonstrate the significance of postmortem tissue samples
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 36(2)
This study investigated and compared the pharmacokinetics of intra-articular (IA) administration of dexamethasone sodium phosphate (DSP) into three equine joints, femoropatellar (IAS), radiocarpal (IAC), and metacarpophalangeal (IAF), and the intramu
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 35(5)
Romifidine HCl (romifidine) is an α(2)-agonist commonly used in horses. This study was undertaken to investigate the pharmacokinetics (PK) of romifidine following intravenous (i.v.) administration and describe the relationship between PK parameters