Zobrazeno 1 - 10
of 65
pro vyhledávání: '"C E, McCall"'
Autor:
J G Giri, J Wells, S K Dower, C E McCall, R N Guzman, J Slack, T A Bird, K Shanebeck, K H Grabstein, J E Sims
Publikováno v:
The Journal of Immunology. 153:5802-5809
Two types of cellular IL-1Rs have been characterized and cloned from both human and murine sources. The type II IL-1R has a very short cytoplasmic domain and does not seem to participate in IL-1 signaling. We demonstrate that type II IL-1Rs are relea
Autor:
K. E. A. Larue, C. E. Mccall
Publikováno v:
The Journal of Experimental Medicine
Tolerance to bacterial lipopolysaccharide (LPS, endotoxin) is an adaptive cellular process whereby exposure to endotoxin induces a subsequent hyporesponsive state characterized by decreased levels of LPS-induced cytokine mRNA and protein. We demonstr
Publikováno v:
The Journal of Immunology. 146:3895-3903
In human neutrophils, the chemotactic tripeptide FMLP and the protein kinase C activator PMA stimulate the breakdown of 1-O-[3H]alkyl-2-acyl-sn-glycero-3-phosphocholine ([3H]EAPC) and the formation of 1-O-[3H]alkyl-2-acyl-phosphatidic acid ([3H]-EAPA
Publikováno v:
Journal of Clinical Investigation. 87:1312-1321
Expression of IL-1 alpha and beta genes was studied in human blood PMN with close monitoring of the effects of contaminating mononuclear leukocytes (MNL). We provide evidence that PMN both transcribe and translate IL-1 alpha and beta genes after stim
Publikováno v:
The Journal of Immunology. 146:1277-1285
The cytokine, TNF-alpha, interacts with human neutrophils (PMN) via specific membrane receptors and primes leukotriene B4 (LTB4) production in PMN for subsequent stimulation by calcium ionophores. We have further examined the effects of TNF-alpha on
Publikováno v:
The Journal of biological chemistry. 268(32)
NADPH oxidase, the respiratory burst enzyme of human neutrophils, is a multi-component complex that is assembled and activated during stimulation of the cells by inflammatory or phagocytic stimuli. The signal mechanisms leading to activation of the e
Publikováno v:
The Journal of biological chemistry. 267(28)
Propranolol, a beta-adrenergic receptor antagonist, also inhibits phosphatidate phosphohydrolase, the enzyme that converts phosphatidic acid into diacylglycerol. This latter effect has prompted recent use of propranolol in studies examining the impor
Publikováno v:
The Journal of biological chemistry. 267(21)
We report here that lipopolysaccharide (LPS) priming of rabbit alveolar macrophages leads to amplified synthesis of prostanoids, at least in part, by induction of a novel prostaglandin H synthase (PGH synthase). Rabbit alveolar macrophages were cultu
Publikováno v:
The Journal of biological chemistry. 266(7)
Tumor necrosis factor alpha (TNF) primes human neutrophils (PMN) for enhanced superoxide (O2-) production if cells are subsequently stimulated with the chemotactic peptide, n-formyl-Met-Leu-Phe (fMLP). fMLP activates phospholipase D to form phosphati
Autor:
C E McCall, W L Salzer
Bacterial sepsis often precedes the development of the adult respiratory distress syndrome (ARDS) and bacterial endotoxin (LPS) produces a syndrome similar to ARDS when infused into experimental animals. We determined in isolated, buffer-perfused rab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1053aba56685ada8bbb7b437cf661b
https://europepmc.org/articles/PMC296544/
https://europepmc.org/articles/PMC296544/