Zobrazeno 1 - 9 of 9 pro vyhledávání: '"C E, Egwuagu"'
1
Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals
Autor: C. E. Egwuagu, Althaf Lohani, Michele K. Evans, Andrzej R. Trzeciak, Cheng-Rong Yu, Mahdi Rm, Xuebin Liu
Publikováno v: Oncogene. 26:1941-1948
DNA-hypermethylation of SOCS genes in breast, ovarian, squamous cell and hepatocellular carcinoma has led to speculation that silencing of SOCS1 and SOCS3 genes might promote oncogenic transformation of epithelial tissues. To examine whether transcri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4b2c30c2b6797f0c6d2f2923d25ad6
https://doi.org/10.1038/sj.onc.1209993
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2
Thymic expression of autoantigens correlates with resistance to autoimmune disease
Autor: C E Egwuagu, P Charukamnoetkanok, I Gery
Publikováno v: The Journal of Immunology. 159:3109-3112
Experimental autoimmune uveoretinitis (EAU), an animal model for human intraocular inflammation (uveitis), is induced by immunization with retinal proteins such as S-Ag or interphotoreceptor retinoid binding protein. Marked differences exist among di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa9b64aa7d5e7d73108db109ec5ee8b2
https://doi.org/10.4049/jimmunol.159.7.3109
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3
Evidence for selective accumulation of V beta 8+ T lymphocytes in experimental autoimmune uveoretinitis induced with two different retinal antigens
Autor: C E Egwuagu, R M Mahdi, R B Nussenblatt, I Gery, R R Caspi
Publikováno v: The Journal of Immunology. 151:1627-1636
Experimental autoimmune uveoretinitis (EAU) is a T cell-mediated autoimmune disease that serves as a model of human intraocular inflammatory disease (uveitis) and is initiated in susceptible animals by immunization with retinal Ag, such as interphoto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::184a014efdbd695ec1f30af990bb8280
https://doi.org/10.4049/jimmunol.151.3.1627
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4
Interferon-gamma induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors
Autor: Wenmei Li, T. Nakamura, C. E. Egwuagu, Cheng-Rong Yu, C.-C. Chan, M. Che Mei Lin, A. B. Chepelinsky
Publikováno v: Oncogene. 25(26)
We have developed an epithelial cell carcinoma model for studying efficacy of IFNgamma gene therapy and have identified components of IFNgamma-signaling pathway responsible for its direct anti-tumor actions. The tumor results from ectopic expression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71ccedff5cb40e7388dc152f876b432
https://pubmed.ncbi.nlm.nih.gov/16462767
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5
Interferon-gamma signaling in human retinal pigment epithelial cells mediated by STAT1, ICSBP, and IRF-1 transcription factors
Autor: W, Li, C N, Nagineni, J J, Hooks, A B, Chepelinsky, C E, Egwuagu
Publikováno v: Investigative ophthalmologyvisual science. 40(5)
Studies have shown that interferon (IFN)-gamma stimulates expression of intercellular adhesion molecule-1 (ICAM-1), major histocompatibility complex (MHC) class II, interleukin (IL)-6, and inducible nitric oxide synthase and inhibits replication of T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c1eb63549c12c1ba4a9f1ddf20ce0f7f
https://pubmed.ncbi.nlm.nih.gov/10102295
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6
Immunotolerance against a foreign antigen transgenically expressed in the lens
Autor: J C, Lai, A, Fukushima, E F, Wawrousek, M C, Lobanoff, P, Charukamnoetkanok, S J, Smith-Gill, B P, Vistica, R S, Lee, C E, Egwuagu, S M, Whitcup, I, Gery
Publikováno v: Investigative ophthalmologyvisual science. 39(11)
To extend our knowledge concerning immunotolerance against autologous lens crystallins, transgenic (Tg) mice that express a foreign antigen in their lens were generated, and the immune response against the antigen in these mice was analyzed.Conventio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7eda457157d0d043ebc7791eb968405
https://pubmed.ncbi.nlm.nih.gov/9761283
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8
Synthesis and analysis of the enantiomers of calmidazolium, and a 1H NMR demonstration of a chiral interaction with calmodulin
Autor: A J, Edwards, P J, Sweeney, D G, Reid, J M, Walker, N, Elshourbagy, C E, Egwuagu, J F, Young, C L, Patton
Publikováno v: Chirality. 8(8)
Calmidazolium [R24571, 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4- dichlorophenyl)methoxy]ethyl]-1H-imidazolium chloride] is a potent calmodulin inhibitor. This paper describes the synthesis and properties of the enantiomers of c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9f1e438b0912fe9030acbdca7124370d
https://pubmed.ncbi.nlm.nih.gov/9025254
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9
Differential involvement of Th1 or Th17 cells in pathogenic autoimmune processes triggered by different TLR ligands (129.22)
Autor: G. Shi, B. P. Vistica, C-R. Yu, C. A. Cox, V. Montalvo, E. F. Wawrousek, C. E. Egwuagu, I. Gery
Publikováno v: The Journal of Immunology. 178:S222-S222
We have previously shown that various TLR ligands are capable of converting naïve CD4 cells specific to hen egg lysozyme (HEL) to become effector cells that initiate inflammation in eyes of recipient mice expressing HEL in their lens. In addition,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1962de481b524da0384e25717e743cc2
https://doi.org/10.4049/jimmunol.178.supp.129.22
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