Zobrazeno 1 - 10
of 49
pro vyhledávání: '"C Douglas, Witherspoon"'
Autor:
Shreyasi Choudhury, Christianne E Strang, John J. Alexander, Miranda L. Scalabrino, Julie Lynch Hill, Daniel T. Kasuga, C. Douglas Witherspoon, Sanford L. Boye, Paul D. Gamlin, Shannon Elizabeth Boye
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Purpose: The ability to generate macaque retinas with sortable cell populations would be of great benefit to both basic and translational studies of the primate retina. The purpose of our study was therefore to develop methods to achieve this goal by
Externí odkaz:
https://doaj.org/article/b30c8f83196a4880bb93652e93d7b597
Autor:
Cynthia Owsley, Richard F. Spaide, Srinivas R. Sadda, C. Douglas Witherspoon, Mark E. Clark, Christine A. Curcio, Yuhua Zhang, Xiaolin Wang
Publikováno v:
Ophthalmol Retina
Purpose To describe the progression and regression of individual subretinal drusenoid deposits (SDDs) and surrounding photoreceptors and retina in patients with age-related macular degeneration (AMD) over a 3.5-year period using multimodal imaging in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3008176e21a033dee8d4929a12751a32
https://doi.org/10.1016/j.oret.2019.10.012
https://doi.org/10.1016/j.oret.2019.10.012
Autor:
Christianne E. Strang, Dibyendu Chakraborty, Jim Peterson, Diego Fajardo, Paul D. Gamlin, C. Douglas Witherspoon, Haiyan Jiang, Steven J. Samuelsson, Morgan L. Maeder, Kaitlyn R. Calabro, Shannon E. Boye, Scott Haskett, Sebastian Gloskowski, K. Tyler McCullough, Sanford L. Boye
Publikováno v:
Human Gene Therapy. 30:571-589
Mutations in GUCY2D, the gene encoding retinal guanylate cyclase-1 (retGC1), are the leading cause of autosomal dominant cone-rod dystrophy (CORD6). Significant progress toward clinical application of gene replacement therapy for Leber congenital ama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::392cdcba89da3c2d5c90495d4de8bcec
https://doi.org/10.1089/hum.2018.193
https://doi.org/10.1089/hum.2018.193
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991389
Adeno-associated virus (AAV) has emerged as the vector of choice for delivering genes to the retina. Indeed, the first gene therapy to receive FDA approval in the United States is an AAV-based treatment for the inherited retinal disease, Leber congen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444afdb596553cc78773452a89109363
https://pubmed.ncbi.nlm.nih.gov/30783978
https://pubmed.ncbi.nlm.nih.gov/30783978
Autor:
K Tyler, McCullough, Sanford L, Boye, Diego, Fajardo, Kaitlyn, Calabro, James J, Peterson, Christianne E, Strang, Dibyendu, Chakraborty, Sebastian, Gloskowski, Scott, Haskett, Steven, Samuelsson, Haiyan, Jiang, C Douglas, Witherspoon, Paul D, Gamlin, Morgan L, Maeder, Shannon E, Boye
Publikováno v:
Hum Gene Ther
Mutations in GUCY2D, the gene encoding retinal guanylate cyclase-1 (retGC1), are the leading cause of autosomal dominant cone–rod dystrophy (CORD6). Significant progress toward clinical application of gene replacement therapy for Leber congenital a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1cf316d5aca359e15a75ee8460f80921
https://pubmed.ncbi.nlm.nih.gov/30358434
https://pubmed.ncbi.nlm.nih.gov/30358434
Autor:
Yuhua Zhang, C. Douglas Witherspoon, Christine A. Curcio, Pooja Godara, Mark E. Clark, Tianjiao Zhang, Xiaolin Wang, Richard F. Spaide, Cynthia Owsley
Purpose To investigate the natural history of dot subretinal drusenoid deposits (SDD) in age-related macular degeneration, using high-resolution adaptive optics scanning laser ophthalmoscopy. Methods Six eyes of four patients with intermediate age-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2007de7252464808567f76c03091f4a
https://europepmc.org/articles/PMC5552451/
https://europepmc.org/articles/PMC5552451/
Autor:
Artur V. Cideciyan, Mychajlo S. Kosyk, John J. Alexander, C. Douglas Witherspoon, Gustavo D. Aguirre, Samuel G. Jacobson, Luis Felipe Marinho, Jeffrey D. Chulay, Guo-jie Ye, Simone Iwabe, Valerie L. Dufour, Jim Peterson, Sanford L. Boye, Malgorzata Swider, Shannon E. Boye, William W. Hauswirth, Mark S. Shearman, Gui-Shuang Ying, William A. Beltran, Paul D. Gamlin, Jin Sha
X-linked retinitis pigmentosa (XLRP) caused by mutations in the RPGR gene is an early onset and severe cause of blindness. Successful proof-of-concept studies in a canine model have recently shown that development of a corrective gene therapy for RPG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffbb67ea248b10a8740ed58311ae139
https://europepmc.org/articles/PMC5542804/
https://europepmc.org/articles/PMC5542804/
Autor:
C. Douglas Witherspoon, Daniel T. Kasuga, John J. Alexander, Shannon E. Boye, Paul D. Gamlin, Julie Lynch Hill, Miranda L. Scalabrino, Sanford L. Boye, Shreyasi Choudhury, Christianne E. Strang
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Frontiers in Neuroscience
Frontiers in Neuroscience
Purpose: The ability to generate macaque retinas with sortable cell populations would be of great benefit to both basic and translational studies of the primate retina. The purpose of our study was therefore to develop methods to achieve this goal by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5195d7b25a1ead72e26233899d671fd2
http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00551/full
http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00551/full
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 252:347-357
To evaluate origins of the fibrocontractive cell populations and their relation to collagens I and II in proliferative vitreoretinopathy (PVR). Human PVR membranes were evaluated by indirect immunofluorescence for GFAP, cytokeratin-18 (CK-18), α-smo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd5b5b5c705177667ae4d6881f1964d
https://doi.org/10.1007/s00417-013-2531-0
https://doi.org/10.1007/s00417-013-2531-0
Autor:
Julia A. Haller, C. Douglas Witherspoon, Cynthia Owsley, Zachary Keenum, Gerald McGwin, Mark E. Clark
Publikováno v:
JAMA ophthalmology. 134(11)
Importance The public health success of diabetic retinopathy (DR) screening programs depends on patients’ adherence to the timetable of follow-up eye care recommended by the screening program. African Americans are among those at highest risk for D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6910624eab1701f2529772b4b066f35
https://pubmed.ncbi.nlm.nih.gov/27631839
https://pubmed.ncbi.nlm.nih.gov/27631839