Zobrazeno 1 - 10
of 1 051
pro vyhledávání: '"C Davenport"'
Autor:
Laura Simões de Oliveira, Heather E. O’Leary, Sarfaraz Nawaz, Rita Loureiro, Elizabeth C. Davenport, Paul Baxter, Susana R. Louros, Owen Dando, Emma Perkins, Julien Peltier, Matthias Trost, Emily K. Osterweil, Giles E. Hardingham, Michael A. Cousin, Sumantra Chattarji, Sam A. Booker, Tim A. Benke, David J. A Wyllie, Peter C. Kind
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Mutations in the X-linked gene cyclin-dependent kinase-like 5 (CDKL5) cause a severe neurological disorder characterised by early-onset epileptic seizures, autism and intellectual disability (ID). Impaired hippocampal function has
Externí odkaz:
https://doaj.org/article/ae255dae432e41748c4459655b5be30f
Autor:
C Meads, P Auguste, C Davenport, S Małysiak, S Sundar, M Kowalska, A Zapalska, P Guest, S Thangaratinam, P Martin-Hirsch, E Borowiack, P Barton, T Roberts, K Khan
Publikováno v:
Health Technology Assessment, Vol 17, Iss 12 (2013)
Background: Cancer of the uterine cervix is a common cause of mortality in women. After initial treatment women may be symptom free, but the cancer may recur within a few years. It is uncertain whether it is more clinically effective to survey asympt
Externí odkaz:
https://doaj.org/article/65b7263bd7954069a2e585456d3306c5
Autor:
M Pennant, Y Takwoingi, L Pennant, C Davenport, A Fry-Smith, A Eisinga, L Andronis, T Arvanitis, J Deeks, C Hyde
Publikováno v:
Health Technology Assessment, Vol 14, Iss 50 (2010)
Background: Breast cancer (BC) accounts for one-third of all cases of cancer in women in the UK. Current strategies for the detection of BC recurrence include computed tomography (CT), magnetic resonance imaging (MRI) and bone scintigraphy. Positron
Externí odkaz:
https://doaj.org/article/58136c37938444cc94ea386a06e81f5b
Publikováno v:
Health Technology Assessment, Vol 12, Iss 18 (2008)
Externí odkaz:
https://doaj.org/article/c643133181b84179971f535c26ca062b
Autor:
J Dretzke, E Frew, C Davenport, J Barlow, S Stewart-Brown, J Sandercock, S Bayliss, J Raftery, C Hyde, R Taylor
Publikováno v:
Health Technology Assessment, Vol 9, Iss 50 (2005)
Externí odkaz:
https://doaj.org/article/560cedc71d274cdfbacf1d523502bd97
Autor:
Katherine Bonnycastle, Katharine L. Dobson, Eva-Maria Blumrich, Akshada Gajbhiye, Elizabeth C. Davenport, Marie Pronot, Moritz Steinruecke, Matthias Trost, Alfredo Gonzalez-Sulser, Michael A. Cousin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Dynamin-1 is a large GTPase with an obligatory role in synaptic vesicle endocytosis at mammalian nerve terminals. Heterozygous missense mutations in the dynamin-1 gene (DNM1) cause a novel form of epileptic encephalopathy, with pathogenic mu
Externí odkaz:
https://doaj.org/article/978480a973bf49a58749c29e55169d7b
Publikováno v:
Health Technology Assessment, Vol 8, Iss 44 (2004)
Externí odkaz:
https://doaj.org/article/968ca56a20dd4e8eac7c90341b5535ee
Autor:
Lisa Ong, Wei Harn Tan, Lisa C. Davenport, Kim R. McConkey, Mohamad Khairul Adha bin Mat Amin, Ahimsa Campos-Arceiz, John W. Terborgh
Publikováno v:
Frontiers in Forests and Global Change, Vol 6 (2023)
Megaherbivores exert strong top-down influence on the ecosystems they inhabit, yet little is known about the foraging impacts of Asian elephants (Elephas maximus) on the structure of Southeast Asia’s rainforests. Our goal was to document Asian elep
Externí odkaz:
https://doaj.org/article/cda24cd197b048baa781b557f91146fe
Autor:
Eva-Maria Blumrich, Jessica C. Nicholson-Fish, Marie Pronot, Elizabeth C. Davenport, Dominic Kurian, Adam Cole, Karen J. Smillie, Michael A. Cousin
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112633- (2023)
Summary: Phosphatidylinositol 4-kinase IIα (PI4KIIα) generates essential phospholipids and is a cargo for endosomal adaptor proteins. Activity-dependent bulk endocytosis (ADBE) is the dominant synaptic vesicle endocytosis mode during high neuronal
Externí odkaz:
https://doaj.org/article/a37b7a0168bf4df7ad2163b7594eb7f3
Autor:
Christiana Kontaxi, Daniela Ivanova, Elizabeth C. Davenport, Peter C. Kind, Michael A. Cousin
Publikováno v:
The Journal of Neuroscience. 43:2002-2020
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a severe early-onset epileptic encephalopathy resulting mainly fromde novomutations in the X-linkedCDKL5gene. To determine whether loss of presynaptic CDKL5 function contributes to C