Zobrazeno 1 - 10 of 401 pro vyhledávání: '"C D Holdsworth"'
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Improved maintenance of remission in ulcerative colitis by balsalazide 4 g/day compared with 2 g/day
Autor: C. A. Rodrigues, C. D. Holdsworth, J. H. Baron, A. M. Hoare, R. J. Polson, Peter McIntyre, S. Manjunatha, M. H. Giaffer, I. G. Barrison, P. C. Thornton, John E. Lennard-Jones, G. S. R. Davies
Publikováno v: Alimentary Pharmacology & Therapeutics. 6:479-485
The efficacy of two doses of balsalazide for the maintenance of remission in patients with ulcerative colitis was compared in a double-blind multicentre trial. Sixty-five patients received a 2 g daily dose, and 68 a 4 g dose. The patient groups were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766292a54e521f49f9f3b1883f3ebedc
https://doi.org/10.1111/j.1365-2036.1992.tb00561.x
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3
A double-blind comparison of balsalazide, 6.75 g, and sulfasalazine, 3 g, as sole therapy in the management of ulcerative colitis
Autor: P. C. Thornton, D. Mckenna, John C. Mansfield, M. H. Giaffer, C. D. Holdsworth, P. A. Cann
Publikováno v: Alimentary Pharmacology & Therapeutics. 16:69-77
Background: Sulfasalazine is accepted therapy for active ulcerative colitis, but side-effects and intolerance are common. Balsalazide is an azo-bonded pro-drug which also releases 5-aminosalicylic acid into the colon, but uses an inert carrier molecu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f5b032b27611b331c68e806a91beae2
https://doi.org/10.1046/j.1365-2036.2002.01151.x
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4
Akademický článek
Rifaximin and alternative agents in the management of irritable bowel syndrome: A comprehensive review.
Autor: Deljavan Ghodrati A; Department of Pharmaceutical Technology, Ankara University Faculty of Pharmacy, Ankara, Turkey.; Graduate School of Health Sciences, Ankara University, Ankara, Turkey., Comoglu T; Department of Pharmaceutical Technology, Ankara University Faculty of Pharmacy, Ankara, Turkey.
Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Oct; Vol. 357 (10), pp. e2400356. Date of Electronic Publication: 2024 Jul 23.
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6
Maintenance of remission of ulcerative colitis: a comparison between balsalazide 3 g daily and mesalazine 1.2 g daily over 12 months
Autor: J. P. Crowe, M. D. Taylor, Alan J Lobo, K. J. Schofield, E. T. Swarbrick, C. D. Holdsworth, G. D. Kerr, J. R. B. Green, J. A. Gibson
Publikováno v: Alimentary Pharmacology & Therapeutics. 12:1207-1216
Background: Despite widespread use of aminosalicylates as maintenance treatment for ulcerative colitis (UC), patients still report troublesome symptoms, often nocturnally. Aim: To compare the efficacy and safety of balsalazide (Colazide) with mesalaz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e03bc7f879b119e5bcbed436315e8cb
https://doi.org/10.1046/j.1365-2036.1998.00427.x
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7
Quantitative assessment of overall inflammatory bowel disease activity using labelled leucocytes: a direct comparison between indium-111 and technetium-99m HMPAO methods
Autor: W B Tindale, C. D. Holdsworth, John C. Mansfield, M. H. Giaffer
Publikováno v: Gut. 37:679-683
The ideal imaging method in inflammatory bowel disease would reliably detect inflammation, identify the correct intestinal location, and assess the severity of the disease. The aim of this study was to compare scintigraphic methods of quantifying ove
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5547e6c02cdc1f4dee24a03013911470
https://doi.org/10.1136/gut.37.5.679
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8
Controlled trial of oligopeptide versus amino acid diet in treatment of active Crohn's disease
Autor: C. D. Holdsworth, M. H. Giaffer, John C. Mansfield
Publikováno v: Gut. 36:60-66
Elemental diets are effective in inducing remission in active Crohn's disease, but how they exert this therapeutic effect is unclear. In a previous study a whole protein containing diet proved less effective than one in which food antigens were exclu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f9ee27800c478924920964b670fec0
https://doi.org/10.1136/gut.36.1.60
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9
Background Subtraction: A New Approach to the Assessment of Disease Activity in Crohn's Disease Using99mTc-HMPAO-Labelled Leucocytes
Autor: C. D. Holdsworth, M. H. Giaffer, W. B. Tindale
Publikováno v: Scandinavian Journal of Gastroenterology. 29:55-60
A computer-based technique for the quantification of abnormal bowel uptake in Crohn's disease has been developed and compared with pre-existing clinical, laboratory and scintigraphic methods of assessment. The standard technique for labelling leucocy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c95f421665ce19308427d475b5dea56
https://doi.org/10.3109/00365529409091398
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10
Quantification of disease activity in Crohn's disease by computer analysis of Tc-99m hexamethyl propylene amine oxime (HMPAO) labelled leucocyte images
Autor: W B Tindale, C. D. Holdsworth, S Senior, D C Barber, M. H. Giaffer
Publikováno v: Gut. 34:68-74
The reliability and clinical applications of computerised image analysis measurement of bowel uptake of Tc-99m HMPAO labelled leucocytes has been examined as a measure of disease activity in Crohn's disease. In 54 studies carried out on 33 patients w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12d88689fa3d7a8f6c9f6737e886fee
https://doi.org/10.1136/gut.34.1.68
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