Výsledky vyhledávání - "C D Bloomfield"

Escalation of daunorubicin and addition of etoposide in the ADE regimen in acute myeloid leukemia patients aged 60 years and older: Cancer and Leukemia Group B Study 9720

Autor: M R, Baer, S L, George, B L, Sanford, K, Mrózek, J E, Kolitz, J O, Moore, R M, Stone, B L, Powell, M A, Caligiuri, C D, Bloomfield, R A, Larson, John, Lister

Publikováno v: Leukemia. 25:800-807

Untreated de novo (n=421) and secondary (n=189) acute myeloid leukemia (AML) patients≥60 years received intensified chemotherapy, including daunorubicin 60mg/m2 and etoposide 100mg/m2 during days 1, 2, 3 with cytarabine 100mg/m2 during days 1–7,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2056b9e72fe5cc2bb06f2714c04fc2a5
https://doi.org/10.1038/leu.2011.9

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Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study (8762)

Autor: C A, Westbrook, A L, Hooberman, C, Spino, R K, Dodge, R A, Larson, F, Davey, D H, Wurster-Hill, R E, Sobol, C, Schiffer, C D, Bloomfield

Publikováno v: Blood. 80:2983-2990

The Philadelphia (Ph1) chromosome, or its molecular counterpart, the BCR-ABL fusion gene, is a rare but important prognostic indicator in childhood acute lymphoblastic leukemia (ALL), but its impact on adult ALL has not been well ascertained. A prosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ec491c58cf287f18a697d3d61ee042
https://doi.org/10.1182/blood.v80.12.2983.bloodjournal80122983

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Spectral karyotyping reveals 17;22 fusions in a cytogenetically atypical dermatofibrosarcoma protuberans with a large marker chromosome as a sole abnormality

Autor: K, Mrózek, M, Iliszko, J, Ryś, M, Babińska, A, Niezabitowski, C D, Bloomfield, J, Limon

Publikováno v: Genes, chromosomescancer. 31(2)

The presence of an extra ring chromosome containing material from 17q and 22q, or, less frequently, a t(17;22)(q22;q13), is a cytogenetic hallmark of dermatofibrosarcoma protuberans (DFSP). However, occasionally tumors with other, atypical karyotypes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ecc4fa4669d7c85561d9fb6ce074e322
https://pubmed.ncbi.nlm.nih.gov/11319805

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Prognostic value of cytogenetic findings in adults with acute myeloid leukemia

Autor: K, Mrózek, K, Heinonen, C D, Bloomfield

Publikováno v: International journal of hematology. 72(3)

The majority of adults diagnosed with acute myeloid leukemia (AML) display acquired cytogenetic aberrations at presentation. Numerous recurring chromosomal abnormalities have been and continue to be identified in AML. In many instances, genes altered

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2067d4a3ac184d9cccd4b54e81fc36ea
https://pubmed.ncbi.nlm.nih.gov/11185980

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The partial nontandem duplication of the MLL (ALL1) gene is a novel rearrangement that generates three distinct fusion transcripts in B-cell acute lymphoblastic leukemia

Autor: S P, Whitman, M P, Strout, G, Marcucci, A G, Freud, L L, Culley, N J, Zeleznik-Le, K, Mrózek, K S, Theil, U R, Kees, C D, Bloomfield, M A, Caligiuri

Publikováno v: Cancer research. 61(1)

A partial nontandem duplication (PNTD) of mixed lineage leukemia (MLL) gene is described in B-cell acute lymphoid leukemia without structural cytogenetic abnormalities at 11q23 and 9p22. A duplicated portion of MLL is interrupted by the insertion of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a219c01d1ff1ff1ad08b10c2e8ffcd3
https://pubmed.ncbi.nlm.nih.gov/11196198

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The World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. Report of the Clinical Advisory Committee meeting, Airlie House, Virginia, November, 1997

Autor: N L, Harris, E S, Jaffe, J, Diebold, G, Flandrin, H K, Muller-Hermelink, J, Vardiman, T A, Lister, C D, Bloomfield

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology. 10(12)

Since 1995, the European Association of Pathologists (EAHP) and the Society for Hematopathology (SH) have been developing a new World Health Organization (WHO) Classification of hematologic malignancies. The classification includes lymphoid, myeloid,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30ba912547b6df11971307a34c9cd512
https://pubmed.ncbi.nlm.nih.gov/10643532

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Prospective karyotype analysis in adult acute lymphoblastic leukemia: the cancer and leukemia Group B experience

Autor: M, Wetzler, R K, Dodge, K, Mrózek, A J, Carroll, R, Tantravahi, A W, Block, M J, Pettenati, M M, Le Beau, S R, Frankel, C C, Stewart, T P, Szatrowski, C A, Schiffer, R A, Larson, C D, Bloomfield

Publikováno v: Blood. 93(11)

The Cancer and Leukemia Group B (CALGB) has been conducting a prospective cytogenetic companion study (CALGB 8461) to all CALGB treatment protocols for newly diagnosed adults with acute lymphoblastic leukemia (ALL). These protocols underwent a signif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72f09e97e973a19c11e465c1dd739109
https://pubmed.ncbi.nlm.nih.gov/10339508

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