Zobrazeno 1 - 10
of 41
pro vyhledávání: '"C D, Strader"'
Autor:
B. Arison, R. Hirschmann, J. Salvino, W. C. Shakespeare, P. G. Spoors, A. B. Smith, Kyriacos C. Nicolaou, W. Vale, P. A. Sprengeler, Peter Hamley, M. R. Cascieri, M. A. Cichy, S. Pietranico, E. M. Leahy, C. D. Strader, R. M. Freidinger, C. Donaldson, T. Reisine, K. Raynor, L. Maechler
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b3b4550441309835a38913647309d37
https://doi.org/10.1002/chin.199415276
https://doi.org/10.1002/chin.199415276
Publikováno v:
Journal of Biological Chemistry. 266:10807-10812
In some G-protein-coupled receptors (e.g. beta-adrenergic receptor (beta 2 AR)), the ligand-binding pocket is contained within the hydrophobic transmembrane domain. In others (e.g. luteinizing hormone receptor (LHR)), the relative roles of the extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a72ae4b6d994b3119f90ad250382eaea
https://doi.org/10.1016/s0021-9258(18)99090-3
https://doi.org/10.1016/s0021-9258(18)99090-3
Autor:
M Van Heek, D S Compton, C F France, R P Tedesco, A B Fawzi, M P Graziano, E J Sybertz, C D Strader, H R Davis
Publikováno v:
The Journal of clinical investigation. 99(3)
Leptin administration reduces obesity in leptin-deficient ob/ob mice; its effects in obese humans, who have high circulating leptin levels, remain to be determined. This longitudinal study was designed to determine whether diet-induced obesity in mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35550cc929cc9d7f31a6a215c7b13694
https://pubmed.ncbi.nlm.nih.gov/9022070
https://pubmed.ncbi.nlm.nih.gov/9022070
Publikováno v:
Molecular pharmacology. 48(3)
The beta 3-adrenergic receptor (beta 3AR) is a member of the super-family of G protein-coupled receptors that are characterized by seven putative transmembrane helices connected by hydrophilic loops. The mechanism by which the activated beta ARs tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41e0a983ba0c694721921262a61b57f0
https://pubmed.ncbi.nlm.nih.gov/7565630
https://pubmed.ncbi.nlm.nih.gov/7565630
Autor:
C. D. Strader, Tung Ming Fong, M. A. Cascieri, R.-R. C. Huang, D. Underwood, C. J. Swain, Hong Yu
Publikováno v:
Canadian journal of physiology and pharmacology. 73(7)
The interactions of the NK1receptor with peptide agonists or nonpeptide antagonists have been investigated by site-directed mutagenesis and computer modeling. At least 10 residues in the extracellular and transmembrane regions of the receptor are req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae782f8007cbbe20c36f8a1f682088a3
https://pubmed.ncbi.nlm.nih.gov/8846422
https://pubmed.ncbi.nlm.nih.gov/8846422
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 9(9)
The family of G-protein-coupled receptors can be defined by their similar structural and functional characteristics. Although their primary sequences are quite diverse, these proteins share several common structural features that reflect their common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d393b0c56235e2829cc590a80456f5d5
https://pubmed.ncbi.nlm.nih.gov/7601339
https://pubmed.ncbi.nlm.nih.gov/7601339
Publikováno v:
Molecular pharmacology. 47(5)
The mechanism by which the hormones 5 alpha-dihydrotestosterone and testosterone differentially regulate such diverse functions as development of male internal and external genitalia and maintenance of prostatic growth via a single androgen receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e41fc5b9f76a5408597b6cb3c4c63787
https://pubmed.ncbi.nlm.nih.gov/7746275
https://pubmed.ncbi.nlm.nih.gov/7746275
Autor:
M A, Cascieri, L L, Shiao, S G, Mills, M, MacCoss, C J, Swain, H, Yu, E, Ber, S, Sadowski, M T, Wu, C D, Strader
Publikováno v:
Molecular pharmacology. 47(4)
We recently described a novel series of diacylpiperazine antagonists of the human neurokinin (NK)-1 receptor. The diacylpiperazine compounds are structurally dissimilar from previously described NK-1 antagonists. L-161,664 [1-(N,N-diphenylaminocarbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a92815a96f743027352fabb9b4d564a
https://pubmed.ncbi.nlm.nih.gov/7536886
https://pubmed.ncbi.nlm.nih.gov/7536886
Autor:
J G, Menke, J A, Borkowski, K K, Bierilo, T, MacNeil, A W, Derrick, K A, Schneck, R W, Ransom, C D, Strader, D L, Linemeyer, J F, Hess
Publikováno v:
The Journal of biological chemistry. 269(34)
A cDNA clone encoding a human B1 bradykinin receptor was isolated from a human embryonic lung fibroblast cDNA library by expression cloning. The photoprotein aequorin was utilized as an indicator of the ability of the B1 receptor agonist [des-Arg10]k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b45b5cf8a633e809083ea25e8ecff372
https://pubmed.ncbi.nlm.nih.gov/8063797
https://pubmed.ncbi.nlm.nih.gov/8063797
Publikováno v:
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 27(8)
A human B2 bradykinin receptor cDNA was cloned from the lung fibroblast cell line, CCD-Lu. This clone was utilized to isolate a genomic clone of a mouse B2 bradykinin receptor. Both clones encode a protein that has the predicted characteristics of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a6d2f47ec45de441918057c731796cf
https://pubmed.ncbi.nlm.nih.gov/7749364
https://pubmed.ncbi.nlm.nih.gov/7749364