Zobrazeno 1 - 10
of 32
pro vyhledávání: '"C D, Fitch"'
Publikováno v:
Journal of Clinical Investigation. 68:672-677
Incubation of a 0.5% suspension of washed, normal mouse erythrocytes with ferriprotoporphyrin IX (FP) at 37 degrees C and pH 7.4 caused potassium loss, swelling, increased susceptibility to hypotonic lysis, and finally hemolysis. Hemolysis was not in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1222eee10520124f66cd8bd6cb4ec5f3
https://doi.org/10.1172/jci110302
https://doi.org/10.1172/jci110302
Publikováno v:
Blood. 52:187-195
Rabbits fed a vitamin E-deficient diet developed severe muscular dystrophy in 3–4 wk, but they did not become anemic. Nevertheless, reticulocyte counts increased in deficient rabbits (3.2%) compared to control rabbits (0.9%), and erythroid hyperpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ca480d1bbe2b1340e90b4e4e85b22a
https://doi.org/10.1182/blood.v52.1.187.bloodjournal521187
https://doi.org/10.1182/blood.v52.1.187.bloodjournal521187
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 195(3)
[14C]amodiaquin accumulation by washed erythrocyte preparations was characterized to permit comparisons with chloroquine accumulation. Erythrocytes infected with Plasmodium berghei CS (chloroquine-susceptible) accumulate amodiaquin by a saturable pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3c59e5f8b3e9753913f4d435b53c308
https://pubmed.ncbi.nlm.nih.gov/488
https://pubmed.ncbi.nlm.nih.gov/488
Publikováno v:
The American journal of clinical nutrition. 33(6)
Vitamin E deficiency was induced in sexually immature rhesus monkeys by feeding a purified diet for 24 months or longer. Control monkeys received the same diet but were supplemented with 100 mg of d-ct-tocopheryl acetate 3 times weekly. Ferrokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57eec0261bb3e17eca6e8d09549ea215
https://pubmed.ncbi.nlm.nih.gov/6770670
https://pubmed.ncbi.nlm.nih.gov/6770670
Autor:
P, Dutta, C D, Fitch
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 225(3)
Because ferriprotoporphyrin IX (ferriheme, FP) is a lytic agent that can be released by degradation or oxidative denaturation of hemoglobin, we measured the hemolytic responses of human erythrocytes to FP alone or to FP in combination with various me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f11ff250ea71fa156567945bce3f2704
https://pubmed.ncbi.nlm.nih.gov/6602875
https://pubmed.ncbi.nlm.nih.gov/6602875
Publikováno v:
Life sciences. 25(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4049c106f17ab0912ec55cb13f4c805c
https://pubmed.ncbi.nlm.nih.gov/225632
https://pubmed.ncbi.nlm.nih.gov/225632
Autor:
C D, Fitch
Publikováno v:
Ciba Foundation symposium. 94
Chloroquine, quinine, quinacrine and related drugs are effective antimalarial agents only against parasites that degrade haemoglobin. This fact prompted an examination of the role of ferriprotoporphyrin IX (FP), a product of haemoglobin degradation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b33357ece32717265c5d286de0774317
https://pubmed.ncbi.nlm.nih.gov/6341003
https://pubmed.ncbi.nlm.nih.gov/6341003
Publikováno v:
The American journal of clinical nutrition. 39(2)
We conducted a prospective, randomized, double-blind therapeutic trial of vitamin E as an erythropoietic agent in a group of patients with chronic renal failure who were undergoing chronic hemodialysis. Sixteen patients received 400 IU of vitamin E (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f19ea4cc670408dabe3bbb2bdd62ad
https://pubmed.ncbi.nlm.nih.gov/6364774
https://pubmed.ncbi.nlm.nih.gov/6364774
Autor:
C D, Fitch
Publikováno v:
Progress in clinical and biological research. 313
A review of all available evidence supports the hypothesis that FP is the receptor for chloroquine and mediator of its antimalarial activity. In accord with this hypothesis, previously unpublished experiments are described which demonstrate no effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::353d9d031f5b41b8e1da1937c2758a1e
https://pubmed.ncbi.nlm.nih.gov/2675116
https://pubmed.ncbi.nlm.nih.gov/2675116
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 195(3)
The response of [14C]chloroquine accumulation to the provision of substrate was evaluated using washed erythrocytes infected with Plasmodium berghei CS (chloroquine-susceptible), with P. berghei CR (chloroquine-resistant), with Plasmodium vinckei CS,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6df70a1253fa5e42c0907486a32b0234
https://pubmed.ncbi.nlm.nih.gov/1104805
https://pubmed.ncbi.nlm.nih.gov/1104805