Zobrazeno 1 - 6
of 6
pro vyhledávání: '"C D, Conover"'
Publikováno v:
Anti-cancer drug design. 14(6)
The primary purpose of this study was to screen individual amino acid spacers in polyethylene glycol (PEG) conjugated camptothecin for their impact on the conjugates' antitumor activity. Secondly, an active member of this series was used to assess th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c0305449887c95c660140eaa188fcd1
https://pubmed.ncbi.nlm.nih.gov/10834271
https://pubmed.ncbi.nlm.nih.gov/10834271
Publikováno v:
Critical reviews in therapeutic drug carrier systems. 17(2)
Low molecular weight Poly(ethylene glycol) (PEG) (20,000)-drug conjugates, prepared over a 20-year period, have been scrutinized and their properties and efficacy reviewed. No commercial products have thus far been reported for these types of compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9bf692671b8251a59d13178806a08455
https://pubmed.ncbi.nlm.nih.gov/10820646
https://pubmed.ncbi.nlm.nih.gov/10820646
Publikováno v:
Anti-cancer drug design. 13(5)
Synthesis and in vivo antitumor activity evaluation of water-soluble poly(ethylene glycol) (PEG)-conjugated paclitaxel-2'-glycinate (6) are reported. This prodrug demonstrated enhanced antitumor activity and less toxicity in a P388/0 murine leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c90b9bbfba46ae7299c075dcbad92fe1
https://pubmed.ncbi.nlm.nih.gov/9702205
https://pubmed.ncbi.nlm.nih.gov/9702205
Publikováno v:
In vivo (Athens, Greece). 12(2)
Hypoxic tumors are frequently resistant to radiation therapy. Polyethylene glycol conjugated bovine hemoglobin (PEG-Hb) was tested for its ability to increase oxygen tension in the hypoxic rat osteogenic sarcoma UMR-106, murine Lewis lung carcinoma L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae38de290a79bc1beab418be82d483d0
https://pubmed.ncbi.nlm.nih.gov/9627798
https://pubmed.ncbi.nlm.nih.gov/9627798
Publikováno v:
Anticancer research. 17(5A)
This study was designed to assess the efficacy of polyethylene glycol(PEG) conjugated camptothecin, PEG-alpha-camptothecin, a novel water soluble transport form (prodrug) of the naturally derived antitumor drug, 20-(S)-camptothecin.Circulatory retent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::129a63a568a0cb8807e39cb5a6f20cc6
https://pubmed.ncbi.nlm.nih.gov/9413173
https://pubmed.ncbi.nlm.nih.gov/9413173
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 44(5)
Severe hemodilution in large mammals has been used rigorously for the safety and efficacy testing of hemoglobin-based red blood cell substitutes. The effects of hemodilution with polyethylene glycol-modified bovine hemoglobin (PEG-Hb) were investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b07cd685d34ce56c72d57702f52b50db
https://pubmed.ncbi.nlm.nih.gov/8763974
https://pubmed.ncbi.nlm.nih.gov/8763974