Zobrazeno 1 - 10
of 23
pro vyhledávání: '"C D, Brooks"'
Autor:
C D, BROOKS, H W, ULCH
Publikováno v:
The Journal of the International College of Surgeons. 9
Publikováno v:
Clinical Experimental Allergy. 21:583-587
Summary We examined unilaterality of obstruction after acute bilateral nasal allergen provocation in two groups of pollen-sensitive volunteers studied out of season. One group was challenged on one occasion with a threshold allergen dose and on anoth
Autor:
C D, Brooks
Publikováno v:
The Journal of rheumatology. 28(4)
Sulfasalazine (SSZ) has regulatory approval for treatment of inflammatory bowel disease in children and adults, and for use as a slow acting agent in adult rheumatoid arthritis (RA). This report surveys the literature for experience with SSZ in juven
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(9)
An in vitro glucuronidation assay was used to optimize a series of N-hydroxyurea-containing 5-lipoxygenase inhibitors for metabolic stability. The glucuronidation of these compounds in cynomolgus monkey microsomes followed Michaelis-Menten kinetics a
Publikováno v:
British journal of clinical pharmacology. 43(6)
Aims The aim of this study was to establish whether pharmacokinetic differences between two pro-drugs of methylprednisolone (MP) are likely to be of clinical significance. Methods This study was a single-blind, randomized, crossover design comparing
Autor:
R L, Bell, R R, Harris, P E, Malo, J B, Bouska, T K, Shaughnessy, K I, Hulkower, C D, Brooks, G W, Carter
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(3)
Our primary goal has been to discover leukotriene biosynthesis inhibitors with characteristics that are appropriate for use as clinical agents. The success of the use of zileuton in the treatment of asthma led us to explore further the use of the N-h
Autor:
R L, Bell, R R, Harris, J B, Bouska, K I, Hulkower, J, Moore, P, Bhatia, P E, Malo, T, Kalosa, C D, Brooks, G W, Carter
Publikováno v:
Advances in experimental medicine and biology. 433
Autor:
C D, Brooks, A O, Stewart, A, Basha, P, Bhatia, J D, Ratajczyk, J G, Martin, R A, Craig, T, Kolasa, J B, Bouska, C, Lanni
Publikováno v:
Journal of medicinal chemistry. 38(24)
Structure-activity optimization of inhibitory potency and duration of action of N-hydroxyurea containing 5-lipoxygenase inhibitors was conducted. The lipophilic heteroaryl template and the link group connecting the template to the N-hydroxyurea pharm
Publikováno v:
Transplantation. 58(10)
Publikováno v:
Rhinology. 31(4)
Acute nasal allergen challenge produces airway obstruction which varies in amount and timing with the allergen dose delivered. To see whether different mechanisms might contribute variably to mucosal swelling with different amounts of allergen, we ch